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12 studies found for:    "Alagille syndrome"
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Rank Status Study
1 Completed Positional Cloning of the Gene(s) Responsible for Alagille Syndrome
Condition: Alagille Syndrome
Intervention:
2 Recruiting Characterization of Pulmonary Artery Stenoses in Alagille Syndrome - a Medical Record Review
Condition: Alagille Syndrome
Intervention:
3 Active, not recruiting Evaluation of LUM001 in the Reduction of Pruritus in Alagille Syndrome
Condition: Alagille Syndrome
Interventions: Drug: LUM001;   Drug: Placebo
4 Active, not recruiting A Long-Term, Open-Label Study of LUM001 With a Double-Blind, Placebo Controlled, Randomized Drug Withdrawal Period to Evaluate Safety and Efficacy in Children With Alagille Syndrome
Condition: Alagille Syndrome
Interventions: Drug: LUM001;   Drug: Placebo
5 Completed
Has Results
Safety and Efficacy Study of LUM001 in the Treatment of Cholestatic Liver Disease in Patients With Alagille Syndrome
Condition: Alagille Syndrome
Interventions: Drug: LUM001;   Drug: Placebo
6 Active, not recruiting An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Subjects With Alagille Syndrome (ALGS)
Condition: Alagille Syndrome
Intervention: Drug: LUM001
7 Recruiting An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Pediatric Subjects With Alagille Syndrome
Condition: Alagille Syndrome
Intervention: Drug: LUM001
8 Completed Validation of the Itch Reported Outcome (ItchRO) Diaries in Pediatric Cholestatic Liver Disease
Conditions: Alagille Syndrome;   Progressive Familial Intrahepatic Cholestasis
Intervention:
9 Completed Study of Magnesium Sulfate in Children With Reduced Bone Density Secondary to Chronic Cholestatic Liver Disease
Conditions: Alagille Syndrome;   Cholestasis;   Biliary Atresia
Interventions: Drug: magnesium gluconate;   Drug: magnesium sulfate
10 Recruiting Evaluating the Genetic Causes and Progression of Cholestatic Liver Diseases (LOGIC)
Conditions: Liver Diseases;   Alagille Syndrome;   Alpha 1-Antitrypsin Deficiency
Intervention:
11 Completed A Safety and Pharmakokinetic Study of A4250 Alone or in Combination With A3384
Conditions: Orphan Cholestatic Liver Diseases;   Primary Biliary Cirrhosis;   Progressive Familial Intrahepatic Cholestasis;   Alagille Syndrome
Interventions: Drug: A4250;   Drug: CRC (A3384);   Drug: Questran;   Drug: Placebo
12 Not yet recruiting FibroScan™ in Pediatric Cholestatic Liver Disease Study Protocol
Conditions: Biliary Atresia;   Alagille Syndrome;   Alpha1 Anti-Trypsin Deficiency;   Portal Hypertension;   Liver Fibrosis;   Cholestasis
Intervention: Other: Liver Stiffness Measurement (LSM)

Study has passed its completion date and status has not been verified in more than two years.