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You are about to leave ClinicalTrials.gov and go to: The preclinical pharmacology of roflumilast--a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease.Pulm Pharmacol Ther 2010;23:235-56. 10.1016/j.pupt.201 URL: https://doi.org/10.1016/j.pupt.2010.03.011

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