Dendritic Cell Vaccine for Head and Neck Cancer (Dendritic)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00492947|
Recruitment Status : Withdrawn (major amendments in progress)
First Posted : June 27, 2007
Last Update Posted : January 11, 2013
This research study is testing a new treatment of cancer of the head and neck.
This research study is being done to:
- Test the safety of the experimental cancer vaccine made of dendritic cells. An experimental vaccine is one that is not approved by the Food and Drug Administration (FDA).
- To learn what effects (good and bad) the vaccine will have on you and your head and neck cancer.
- To learn if the vaccine will stimulate your body's white blood cells, which are part of your immune system (your body's natural defense system).
|Condition or disease||Intervention/treatment||Phase|
|Squamous Cell Carcinoma of Head and Neck||Biological: dendritic cell vaccine||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||0 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||0608 GCC:Phase I Study of Intra-tumoral Injection of Dendritic Cells for the Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck|
|Study Start Date :||June 2007|
|Estimated Primary Completion Date :||June 2010|
|Estimated Study Completion Date :||June 2012|
Biological: dendritic cell vaccine
- safety [ Time Frame: 5 years ]
- Efficacy as measured by RECIST criteria [ Time Frame: 5 years ]
- Characterize the immune response to the vaccine [ Time Frame: 2 years ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00492947
|United States, Maryland|
|University of Maryland Dept. of Otorhinolaryngology|
|Baltimore, Maryland, United States, 21201|
|Principal Investigator:||Jeffrey Wolf, MD||University of Maryland|