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DNA Typing of HLA-DR/DQ Alleles in Taiwan Chinese With Rheumatic Heart Disease

This study has been completed.
Information provided by:
China Medical University Hospital Identifier:
First received: December 12, 2005
Last updated: November 26, 2010
Last verified: January 2004
The current study was designed to determine whether the HLA-DRB1, DQA1, DQB1 alleles are associated with the risk and the pattern of valve damage of RHD.

Condition Intervention
Rheumatic Heart Disease Procedure: venipuncture to withdraw patient's blood

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Masking: None (Open Label)
Primary Purpose: Diagnostic

Resource links provided by NLM:

Further study details as provided by China Medical University Hospital:

Study Start Date: January 2004
Estimated Study Completion Date: July 2005

Ages Eligible for Study:   Child, Adult, Senior

Inclusion Criteria:

  • 1.Patients with Rheumatic mitral stenosis 2.Chinese Han ethnicity

Exclusion Criteria:

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00264524

Division of cardiology, China Medical University Hospital
Taichung, Taiwan, 403
Sponsors and Collaborators
China Medical University Hospital
Principal Investigator: Hsiang-Tai Chou, MD, PhD China Medical University Hospital
  More Information Identifier: NCT00264524     History of Changes
Other Study ID Numbers: CMU93-M-34
Study First Received: December 12, 2005
Last Updated: November 26, 2010

Keywords provided by China Medical University Hospital:
Rheumatic heart disease, HLA, Genetics, Taiwan

Additional relevant MeSH terms:
Heart Diseases
Rheumatic Diseases
Rheumatic Heart Disease
Cardiovascular Diseases
Musculoskeletal Diseases
Connective Tissue Diseases
Rheumatic Fever
Streptococcal Infections
Gram-Positive Bacterial Infections
Bacterial Infections processed this record on September 25, 2017