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DNA Typing of HLA-DR/DQ Alleles in Taiwan Chinese With Rheumatic Heart Disease

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00264524
Recruitment Status : Completed
First Posted : December 13, 2005
Last Update Posted : November 29, 2010
Information provided by:
China Medical University Hospital

Brief Summary:
The current study was designed to determine whether the HLA-DRB1, DQA1, DQB1 alleles are associated with the risk and the pattern of valve damage of RHD.

Condition or disease Intervention/treatment Phase
Rheumatic Heart Disease Procedure: venipuncture to withdraw patient's blood Not Applicable

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Study Type : Interventional  (Clinical Trial)
Allocation: Non-Randomized
Masking: None (Open Label)
Primary Purpose: Diagnostic
Study Start Date : January 2004
Study Completion Date : July 2005

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Heart Diseases

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   Child, Adult, Older Adult

Inclusion Criteria:

  • 1.Patients with Rheumatic mitral stenosis 2.Chinese Han ethnicity

Exclusion Criteria:


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00264524

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Division of cardiology, China Medical University Hospital
Taichung, Taiwan, 403
Sponsors and Collaborators
China Medical University Hospital
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Principal Investigator: Hsiang-Tai Chou, MD, PhD China Medical University Hospital

Layout table for additonal information Identifier: NCT00264524    
Other Study ID Numbers: CMU93-M-34
First Posted: December 13, 2005    Key Record Dates
Last Update Posted: November 29, 2010
Last Verified: January 2004
Keywords provided by China Medical University Hospital:
Rheumatic heart disease, HLA, Genetics, Taiwan
Additional relevant MeSH terms:
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Rheumatic Heart Disease
Rheumatic Diseases
Heart Diseases
Cardiovascular Diseases
Musculoskeletal Diseases
Connective Tissue Diseases
Rheumatic Fever
Streptococcal Infections
Gram-Positive Bacterial Infections
Bacterial Infections