A Community-Based Intervention With Popular Opinion Leaders (C-POL) in Texas

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00260715
Recruitment Status : Completed
First Posted : December 2, 2005
Last Update Posted : December 2, 2005
Texas A&M University
Information provided by:
Centers for Disease Control and Prevention

Brief Summary:
After exposure to the C-POL intervention: 1) unprotected vaginal or anal sex, sex with casual partners, concurrent sexual relationships, and exchange of sex for drugs or money will decrease significantly; 2) perceived syphilis-risk for self and peer group, knowledge about highly relevant risk-factors, information sources and resources will increase significantly; and 3) syphilis morbidity will decrease significantly in the intervention community as compared to the comparison community.

Condition or disease Intervention/treatment Phase
Risk Behavior Sexually Transmitted Diseases Behavioral: Community-Popular Opinion Leader Model Behavioral: Diffusion of Innovations Not Applicable

Detailed Description:

The C-POL in Texas project is and intervention study which sought to impact the health behaviors of community residents who live in zip codes that have high syphilis morbidity. The study is being implemented in Texas (Dallas and Houston) with residents of a housing developing and the surrounding community.

The intervention model used for this study is the Popular Opinion Leader (POL) model, which is effective at reducing new HIV infections. The intent of this study was to determine the effectiveness of a diffusion model (e.g. POL) at reducing syphilis infections in affected communities.

For the intervention, community members identified as popular opinion leaders were recruited and trained to share accurate information about syphilis transmission, symptoms, testing, treatment and prevention. Prior to intervention implementation and several times after, community members were given a survey and screened for syphilis as well as 2-3 additional STDs. During each assessment, cross-sections of the community members were sampled.

Study Type : Interventional  (Clinical Trial)
Enrollment : 1200 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: A Community-Based Intervention With Popular Opinion Leaders (C-POL) in Texas to Achieve Syphilis Elimination
Study Start Date : October 2002
Study Completion Date : July 2005

Resource links provided by the National Library of Medicine

Primary Outcome Measures :
  1. Change in syphilis prevalence in affected community.

Secondary Outcome Measures :
  1. Change in risk behaviors, and health care seeking.

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Community members who live and/or frequent the affected community. The affected community was one that had significant syphilis morbidity at the onset of the study.

Exclusion Criteria:

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00260715

United States, Texas
Texas A& M University
College Station, Texas, United States, 77843-4243
Sponsors and Collaborators
Centers for Disease Control and Prevention
Texas A&M University
Study Chair: Samantha Williams, Ph.D. CDC/NCHSTP/DSTDP/BIRB
Principal Investigator: Nilesh Chatterjee, Ph.D. Texas A&M University Identifier: NCT00260715     History of Changes
Other Study ID Numbers: CDC-NCHSTP-4133
First Posted: December 2, 2005    Key Record Dates
Last Update Posted: December 2, 2005
Last Verified: December 2005

Keywords provided by Centers for Disease Control and Prevention:
Risk behavior
Sexually Transmitted Diseases

Additional relevant MeSH terms:
Sexually Transmitted Diseases
Virus Diseases
Genital Diseases, Male
Genital Diseases, Female