Treatment of Adolescent Suicide Attempters (TASA)

This study has been completed.
Sponsor:
Collaborator:
Information provided by (Responsible Party):
New York State Psychiatric Institute
ClinicalTrials.gov Identifier:
NCT00080158
First received: March 24, 2004
Last updated: November 1, 2013
Last verified: July 2008
  Purpose

The purpose of this study is to compare the effects of three types of treatments for depressed teenagers who have attempted suicide.


Condition Intervention Phase
Depression
Suicide, Attempted
Drug: fluoxetine
Drug: sertraline
Drug: citalopram
Drug: escitalopram
Drug: bupropion
Drug: mirtazapine
Drug: venlafaxine
Drug: lithium
Behavioral: Cognitive Behavioral Therapy
Phase 2
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment

Resource links provided by NLM:


Further study details as provided by New York State Psychiatric Institute:

Estimated Enrollment: 120
Study Start Date: March 2004
Study Completion Date: June 2007
Detailed Description:

Suicide is the third leading cause of death in adolescents and is a major public health problem. Depression is the most common diagnosis for adolescent suicide attempts. Little is known about what treatment is best for these adolescents since they are usually excluded from participation in research studies.

Participants in this study will be randomly assigned to receive carefully monitored antidepressant medication with routine support and management, cognitive behavioral therapy (CBT), or a combination of antidepressant medication plus CBT.

  Eligibility

Ages Eligible for Study:   12 Years to 18 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • At least one suicide attempt or interrupted attempt within the past 45 days
  • Continuously reside with a primary caretaker (parent, legal guardian, foster parent) for at least 6 months that can provide legal consent
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00080158

Locations
United States, Maryland
Johns Hopkins University
Baltimore, Maryland, United States, 21287
United States, New York
Columbia University at the New York State Psychiatric Institute
New York, New York, United States, 10032
New York University Child Study Center
New York, New York, United States, 10016
United States, North Carolina
Duke University Medical Center
Durham, North Carolina, United States, 27705
United States, Pennsylvania
University of Pittsburgh - Western Psychiatric Institute and Clinic
Pittsburgh, Pennsylvania, United States, 15213
United States, Texas
University of Texas, Southwestern Medical Center
Dallas, Texas, United States, 75235
Sponsors and Collaborators
New York State Psychiatric Institute
Investigators
Study Chair: Laurence Greenhill, MD
  More Information

No publications provided by New York State Psychiatric Institute

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: New York State Psychiatric Institute
ClinicalTrials.gov Identifier: NCT00080158     History of Changes
Obsolete Identifiers: NCT00183534
Other Study ID Numbers: #4623, U10MH066762, U10 MH066775, U10 MH066778, U10 MH066769, U10 MH066750, DDTR B4-ARD
Study First Received: March 24, 2004
Last Updated: November 1, 2013
Health Authority: United States: Food and Drug Administration

Keywords provided by New York State Psychiatric Institute:
Dysthymic Disorder
Adolescent

Additional relevant MeSH terms:
Suicide
Suicide, Attempted
Behavioral Symptoms
Self-Injurious Behavior

ClinicalTrials.gov processed this record on June 30, 2015