Association of Vitamin D, Parathyroid Hormone and Fibroblast Growth Factor-23 With Infarction-related Arrhythmia in Patients With Acute Myocardial Infarction

This study is currently recruiting participants. (see Contacts and Locations)
Verified October 2013 by Yonsei University
Sponsor:
Information provided by (Responsible Party):
Yonsei University
ClinicalTrials.gov Identifier:
NCT01971619
First received: October 23, 2013
Last updated: October 28, 2013
Last verified: October 2013
  Purpose

To investigate the effect of vitamin D deficiency on the development of arrhythmia in patients with acute myocardial infarction.


Condition
Acute Myocardial Infarction

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective

Resource links provided by NLM:


Further study details as provided by Yonsei University:

Primary Outcome Measures:
  • Events of acute myocardial infarction-associated arrhythmia [ Time Frame: first 48 hours after onset of acute myocardial infarction ] [ Designated as safety issue: No ]
    incidence of acute myocardial infarction-associated arrhythmia types of arrhythmia, duration of arrhythmia, persistence of arrhythmia


Biospecimen Retention:   Samples With DNA

plasma blood sample (5ml)


Estimated Enrollment: 510
Study Start Date: August 2013
Estimated Study Completion Date: August 2015
Primary Completion Date: October 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts
SACS cohort
patients with acute myocardial infarction at Severance hospital

  Eligibility

Ages Eligible for Study:   20 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

patients with acute myocardial infarction

Criteria

Inclusion Criteria:

  • age ≥20 years
  • diagnosed with acute myocardial infarction (confirmed by cardiac enzyme and EKG)
  • subjects who agreed with informed consent

Exclusion Criteria:

  • previous history of arrhythmia before onset of acute myocardial infarction
  • currently taking anti-arrhythmic drugs
  • severe condition of comorbid diseases that can cause more serious effects on patients than acute myocardial infarction does (e.g., cancer, cerebrovascular diseases, acute bleeding etc.)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01971619

Contacts
Contact: Jin Wi, MD 82-2-2228-8429 caesar@yuhs.ac

Locations
Korea, Republic of
Department of Internal Medicine, Yonsei University College of Medicine Recruiting
Seoul, Korea, Republic of, 120-752
Contact: Jin Wi, MD    82-2-2228-8429    caesar@yuhs.ac   
Sponsors and Collaborators
Yonsei University
  More Information

Publications:
Responsible Party: Yonsei University
ClinicalTrials.gov Identifier: NCT01971619     History of Changes
Other Study ID Numbers: 4-2013-0424
Study First Received: October 23, 2013
Last Updated: October 28, 2013
Health Authority: Korea: Institutional Review Board

Additional relevant MeSH terms:
Infarction
Myocardial Infarction
Ischemia
Pathologic Processes
Necrosis
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Vascular Diseases

ClinicalTrials.gov processed this record on July 20, 2014