Study the Signs of Ocular Degeneration in a Population Cohort (Dijon 3C Cohort)
The aim of the study proposed in Dijon is above all to focus on the possible relationship between age-related ocular pathologies (AMD and glaucoma) and et les degenerative neurological and cardiac pathologies.
The principal objective is to seek in subjects who have undergone cerebral MRI and echocardiography, associations between the thickness of postganglionic fibers measured by Optical Coherence Tomography at the 7th year (n=1500) and signs of cerebral impairment (psycho-cognitive tests, circulation time, MRI signs). This association will be studied after taking into account the principal environmental (particularly dietary) and genetic risk factors.
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
|Official Title:||Study the Signs of Ocular Degeneration in a Population Cohort (Dijon 3C Cohort): Seek Correlations Between Signs of Neurological and Vascular Degeneration and Signs of Ocular Aging|
- Measure the mean thickness of postganglionic fibers [ Time Frame: T=7 years of the 3C cohort ]Measure the thickness of postganglionic fibers by Optical Coherence Tomography in the 4 quadrants of the peripapillary sclera.
|Study Start Date:||October 2009|
|Estimated Primary Completion Date:||October 2013 (Final data collection date for primary outcome measure)|
|Contact: Catherine CREUZOT-GARCHER||3 80 29 51 73 ext firstname.lastname@example.org|
|Dijon, France, 21000|
|Contact: Catherine CREUZOT-GARCHER 3 80 29 51 73 ext 33 email@example.com|
|Principal Investigator: Catherine CREUZOT-GARCHER|
|Sub-Investigator: Alain BRON|
|Sub-Investigator: Marie PASSEMARD|