Pregnancy Outcome After IVF/ICSI in Endometriosis Patients Stage I and II
In this study of endometriosis patients we compare a common treatment of surgical therapy and medical treatment for 3 months (Zoladex)with patients receiving only surgical therapy. In both cases they immediately start IVF treatment.
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Pregnancy Outcome After IVF/ICSI in Endometriosis Associated Tubal Factor Infertility in Endometriosis Stage I and II. Comparison of Results of IVF After Surgical Therapy Only or After Surgical Vaporisation Associated With Medical Therapy. A Prospective Randomized Study.|
- 2 PN fertilization [ Time Frame: 24 hours after ICSI ] [ Designated as safety issue: No ]laboratory follow up of the fertilized egg during the first 24h
- embryo quality [ Time Frame: 3 to 5 days after egg retrieval ] [ Designated as safety issue: No ]The development of the embryo during the first 3 to 5 days after fertilization.
- pregnancy rate [ Time Frame: 12 weeks ] [ Designated as safety issue: No ]The number of ongoing pregnancies obtained wich still is the most important issue for the patients.
|Study Start Date:||March 2012|
|Estimated Primary Completion Date:||September 2013 (Final data collection date for primary outcome measure)|
Active Comparator: Zoladex
After surgical vaporization of endometriosis patients are treated with Zoladex for 3 months.
after surgical vaporization patients are treated with Zoladex for 3 months
No Intervention: vaporization only
Surgical vaporization of the endometriosis is done and patients start IVF without additional treatment.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01682642
|Contact: Wim Decleer, gynecologist||0032 9 firstname.lastname@example.org|
|Contact: Paul Devroey, professor||0032 9 email@example.com|
|AZ Jan Palfijn||Recruiting|
|Gent, Oost-vlaanderen, Belgium, 9000|
|Contact: Wim Decleer, gynecologist 0032 9 2243024 firstname.lastname@example.org|
|Contact 0032 9 2248850 email@example.com|
|Principal Investigator: Wim Decleer, gynecologist|
|Principal Investigator:||Wim Decleer, gynecologist||IVF Centrum Jan Palfijn Gent|