Lower Extremity Muscle and Function in the Elderly: Study 2

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Roger A Fielding, Tufts University
ClinicalTrials.gov Identifier:
NCT01614392
First received: September 28, 2009
Last updated: June 5, 2012
Last verified: June 2012
  Purpose

This research study is looking to compare the effects of two uniquely different power training interventions (high force, lower velocity versus low force, high velocity) on changes in mobility status among older individuals at risk for mobility disability.


Condition Intervention
Mobility Limitation
Behavioral: Lower Extremity high velocity low force Power Training

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Treatment
Official Title: Lower Extremity Muscle and Function in the Elderly: Study 2

Further study details as provided by Tufts University:

Primary Outcome Measures:
  • Peak lower extremity velocity [ Time Frame: Change from Baseline to Week 4, change from baseline to Week 16 ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Muscle Strength [ Time Frame: Change from Baseline to week 4, change from baseline to Week 16 ] [ Designated as safety issue: No ]

Enrollment: 52
Study Start Date: September 2009
Study Completion Date: October 2011
Primary Completion Date: October 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Lower Extremity Power Training Behavioral: Lower Extremity high velocity low force Power Training
Lower Extremity high velocity, low force Power Training
Other Name: Lower Extremity low velocity, high force power training
Experimental: Lower Extremity power training Behavioral: Lower Extremity high velocity low force Power Training
Lower Extremity high velocity, low force Power Training
Other Name: Lower Extremity low velocity, high force power training

  Eligibility

Ages Eligible for Study:   70 Years to 85 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Male and Female 70-85 yrs
  • Community dwelling
  • Short Performance Battery Score >9
  • BMI range 19-32 kg/m2
  • Willingness to be randomized and come the laboratory for 20 weeks.

Exclusion Criteria:

  • Acute or Terminal Illness
  • MI in previous 6 months, symptomatic coronary artery disease or congestive heart failure.
  • Upper or Lower extremity fracture in previous 6 months
  • Uncontrolled hypertension (150/90mmHg)
  • Neuromuscular diseases and drugs that affect neuromuscular function
  • Hormone replacement therapy
  • Participation in any regular endurance or resistance training exercise during previous 3 months
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01614392

Locations
United States, Massachusetts
Jean Mayer USDA Human Nutrition Research Center on Aging
Boston, Massachusetts, United States, 02111
Sponsors and Collaborators
Tufts University
Investigators
Principal Investigator: Roger A Fieilding, Ph D. Jean Mayer USDA Human Nutrition Research Center on Aging
  More Information

No publications provided

Responsible Party: Roger A Fielding, Director and Senior Scientist, Professor of Nutrition, Jean Mayer USDA Human Nutrition Research Center on Aging., Tufts University
ClinicalTrials.gov Identifier: NCT01614392     History of Changes
Other Study ID Numbers: AG-18844
Study First Received: September 28, 2009
Last Updated: June 5, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by Tufts University:
Resistance Exercise
Physical Activity
Mobility disability
Physical function
Muscle Strength
Older Adults
Mobility-Limited
Peak power and strength

Additional relevant MeSH terms:
Mobility Limitation
Signs and Symptoms

ClinicalTrials.gov processed this record on September 30, 2014