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Effects of Serotonin Inhibitors on Patient-controlled Analgesia Related Nausea and Vomiting

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Hee-Soo Kim, Seoul National University Hospital
ClinicalTrials.gov Identifier:
NCT01517438
First received: January 17, 2012
Last updated: January 20, 2012
Last verified: January 2012
History of Changes
  Purpose

ED50 of dexmedetomidine for prevention of emergence agitation after tonsillectomy or adenoidectomy in children


Condition Intervention
Agitation
 Behavioral: agitation

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Double Blind (Investigator, Outcomes Assessor)
Primary Purpose: Prevention

Resource links provided by NLM:

Drug Information available for: Serotonin
U.S. FDA Resources

Further study details as provided by Seoul National University Hospital:

Primary Outcome Measures:
  • agitation score [ Time Frame: 30 minutes after postoperatuib ] [ Designated as safety issue: No ]
    agitation score


Enrollment: 21
Study Start Date: March 2011
Study Completion Date: December 2011
Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
Intervention Details:
    Behavioral: agitation
    agitation score after desflurane anesthesia
  Eligibility

Ages Eligible for Study:   2 Years to 15 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • tonsillectomy or adenoidectomy

Exclusion Criteria:

  • development delay,
  • CNS abnormality
  Contacts and Locations
No Contacts or Locations Provided
  More Information

No publications provided

Responsible Party: Hee-Soo Kim, Department of Anesthesiology and Pain Medicine, Seoul National University Hospital
ClinicalTrials.gov Identifier: NCT01517438     History of Changes
Other Study ID Numbers: ramosetron
Study First Received: January 17, 2012
Last Updated: January 20, 2012
Health Authority: Korea: Food and Drug Administration

Keywords provided by Seoul National University Hospital:
agitation, desflurane, children

Additional relevant MeSH terms:
Psychomotor Agitation
Dyskinesias
Neurologic Manifestations
Nervous System Diseases
Psychomotor Disorders
Neurobehavioral Manifestations
Signs and Symptoms
 Serotonin Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Serotonin Agents
Physiological Effects of Drugs

ClinicalTrials.gov processed this record on May 21, 2013