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Relationship Between Tissue Markes in Patients With Post Cardio Respiratory Syndrome

This study is currently recruiting participants.
Verified November 2011 by Hospital Nossa Senhora da Conceicao
Sponsor:
Information provided by (Responsible Party):
Vanessa Martins de oliveira, Hospital Nossa Senhora da Conceicao
ClinicalTrials.gov Identifier:
NCT01455662
First received: September 28, 2011
Last updated: November 2, 2011
Last verified: November 2011
History of Changes
  Purpose

There is a correlation between hospital mortality and changes in markers of tissue perfusion, lactate, and venous oxygen saturation and carbon dioxide gradient.


Condition
Cardiac Arrest

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Relationship Between Lactate and Venous Oxygen Saturation Gradient of Carbon Dioxide in Patients With Post Cardio Respiratory Syndrome

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Hospital Nossa Senhora da Conceicao:

Primary Outcome Measures:
  • mortality [ Time Frame: 1 year ] [ Designated as safety issue: Yes ]

Secondary Outcome Measures:
  • correlation of clearance markers of perfusion with the use of vasopressor and positive fluid balance [ Time Frame: 6 hours ] [ Designated as safety issue: Yes ]

Estimated Enrollment: 100
Study Start Date: January 2010
Estimated Study Completion Date: December 2011
Estimated Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts
all patients after cardiac arrest

Detailed Description:

Evaluation of the serum carbon dioxide gradient (GapCO2), central venous saturation (ScvO2) and the clearance of serum lactate (Clac) in predicting hospital mortality after cardiac arrest syndrome (post-PCR).

Prospective study, unicenter - Intensive Care Unit - HNSC. Period: May/2010 to June/2011. Serial assessment of GapCO2 of ScvO2 Clac and the first 72 hours post-PCR. Excluded under 18, survival of less than 6HS, pregnant women, traumatized, post-operative hypothermia and liver disease. T-student test, 95% (p <0.05).

  Eligibility

Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

patients hospitalized in the intensive care unit after cardiopulmonary arrest

Criteria

Inclusion Criteria:

  • All patients hospitalized in the intensive care unit after cardiopulmonary arrest with any pace

Exclusion Criteria:

pregnant women, traumatized, post-operative(less 7 days), hypothermia and liver disease.

  • patients hospitalized in the intensive care unit with more than 6 hours post cardiac arrest
  • less 18 years old
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01455662

Contacts
Contact: Vanessa M Oliveira, MD 05192513723 vanessa.oliveira480@gmail.com
Contact: Diego Riveiro, MD 05184175632 dmriveiro@yahoo.com.br

Locations
Brazil
Conceição Hospital Recruiting
Porto Alegre, Rio Grande do Sul, Brazil
Principal Investigator: Vanessa Oliveira, MD            
Principal Investigator: Diego Riveiro, MD            
Sponsors and Collaborators
Hospital Nossa Senhora da Conceicao
Investigators
Principal Investigator: Vanessa Oliveira, MD Conceição Hospital
Principal Investigator: Diego F Riveiro, MD Hospital Nossa Senhora da Conceição
  More Information

No publications provided

Responsible Party: Vanessa Martins de oliveira, Principal Investigator, Hospital Nossa Senhora da Conceicao
ClinicalTrials.gov Identifier: NCT01455662     History of Changes
Other Study ID Numbers: 10086
Study First Received: September 28, 2011
Last Updated: November 2, 2011
Health Authority: Brazil: Ethics Committee

Keywords provided by Hospital Nossa Senhora da Conceicao:
cardiac arrest

Additional relevant MeSH terms:
Heart Arrest
Heart Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on June 13, 2013