Phenotypic Expressions in a French Pseudoxanthoma-Elasticum Cohort
The cohort is intended to study the phenotypic expressions of the pseudoxanthoma elasticum (PXE) disease in various tissues (eye, skin, arteries, etc).
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Phenotypic Expressions in a French Pseudoxanthoma-Elasticum Cohort|
|Study Start Date:||June 2008|
|Estimated Study Completion Date:||January 2021|
|Estimated Primary Completion Date:||January 2020 (Final data collection date for primary outcome measure)|
This national french cohort is intended to improve our knowledge on the PXE disease. The study of phenotypic expression of the diseases is focused on cutaneous, opthalmologic and vascular tissues. All investigations are included in a yearly follow-up for these patients and collected in a database.
Plasma are also collected for all patients and stored in our clinical research biological center in Angers, including genetic (DNA) material extracted from diagnostic skin biopsy. French Ministry of Teaching and Research Authorisation number for the PXE collection is AC 2008 871. Declarative number is DC 2008 870.
|Contact: Ludovic MARTIN, MD PhD||33(2)41-35-34-19||LuMartin@chu-angers.fr|
|Contact: Georges LEFTHERIOTIS, MD-PHD||33(2)41-35-44-56||GeLeftheriotis@chu-angers.fr|
|University Hospital of Angers||Recruiting|
|Angers, Pays de Loire, France, 49933|
|Contact: Ludovic MARTIN, MD-PhD 33(0)2-41-35-34-19 LuMartin@chu-angers.fr|
|Contact: Georges LEFTHERIOTIS, MD-PhD 33(0)2-41-35-44-56 GeLeftheriotis@chu-angers.fr|
|Sub-Investigator: Georges LEFTHERIOTIS, MD-PHD|
|Sub-Investigator: Pierre ABRAHAM, MD-PHD|
|Sub-Investigator: Fabrice PRUNIER, MD-PHD|
|Sub-Investigator: Jean Marc EBRAN, MD|
|Study Director:||Ludovic MARTIN, MD PhD||UH Angers|