Iron Metabolism in Dragon Boat Athletes

This study has been completed.
Sponsor:
Collaborators:
MVZ für Laboratoriumsmedizin Koblenz
Deutscher Drachenboot Verband e.V.
Information provided by (Responsible Party):
Andree Hillebrecht, University of Giessen
ClinicalTrials.gov Identifier:
NCT01431118
First received: August 31, 2011
Last updated: July 21, 2012
Last verified: July 2012
  Purpose

The purpose of the study is:

  • To investigate the effect of sport-specific stress in the iron metabolism of dragon boat athletes
  • To investigate the effects of sport-specific stress in the activity of pro-hepcidin and hepcidin

Condition Intervention
Anaemia
Other: specific dragon boating training intervention
Other: specific dragon boat intervention

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Diagnostic
Official Title: Iron Metabolism in Dragon Boat Athletes - An Analysis of Changes in Blood Count Parameters Under Sport-specific Stress

Resource links provided by NLM:


Further study details as provided by University of Giessen:

Primary Outcome Measures:
  • change from Baseline in prohepcidin after performing dragonboating [ Time Frame: pre and post exercise intervention at the same day ] [ Designated as safety issue: No ]
    one meassurement of prohepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day


Secondary Outcome Measures:
  • haematocrit [ Time Frame: pre and post exercise intervention at the same day ] [ Designated as safety issue: No ]
    one meassurement of haematocrit immediate before and within three hours after performing two to four specific dragonboat intervention at the same day

  • value of reticulocytes [ Time Frame: pre exercise ] [ Designated as safety issue: No ]
    one meassurement of reticulocytes immediate before performing two to four specific dragonboat interventions

  • value of hypochromic erythrocytes [ Time Frame: pre exercise ] [ Designated as safety issue: No ]
    one meassurement of hypochromic erythrocytes immediate before performing two to four specific dragonboat interventions

  • change from Baseline in serum iron after performing dragonboating [ Time Frame: pre and post exercise intervention at the same day ] [ Designated as safety issue: No ]
    one meassurement of serum iron immediate before and within three hours after performing two to four specific dragonboat interventions at the same day

  • value of transferrin [ Time Frame: pre exercise ] [ Designated as safety issue: No ]
    one meassurement of transferrin immediate before performing two to four specific dragonboat interventions

  • value of transferrin saturation [ Time Frame: pre exercise ] [ Designated as safety issue: No ]
    one meassurement of transferrin saturation immediate before performing two to four specific dragonboat interventions

  • value of ferritin [ Time Frame: pre exercise ] [ Designated as safety issue: No ]
    one meassurement of ferritin immediate before performing two to four specific dragonboat interventions

  • change from Baseline in hepcidin after performing dragonboating [ Time Frame: pre and post exercise intervention at the same day ] [ Designated as safety issue: No ]
    one meassurement of hepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day


Estimated Enrollment: 40
Study Start Date: April 2011
Study Completion Date: April 2012
Primary Completion Date: April 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: sports intervention male
male athletes of the german national dragon boat team
Other: specific dragon boating training intervention
male athletes of the german national dragon boat team performing three specific training units at one day
Active Comparator: sports intervention women
women athletes of the german national dragon boat team
Other: specific dragon boat intervention
women athletes of the german national dragon boat team performing two specific training units and one weight lifting test at one day

Detailed Description:

This investigation evaluates the effects of sport-specific stress in iron metabolism of dragon boat athletes. Recent studies showed a significant increase in hepcidin activity under exercise (Röcker L. et al.(2005): Iron regulatory protein hepcidin is increased in female athletes after a marathon. European Journal of Applied Physiology, S. 95, 569-571)which possibly influences the iron metabolism.

In particular in this investigation the activity of pro-hepcidin and hepcidin under sport-specific stress is analysed. Therefore elite dragonboat athletes will be included to this study. Every athlete is tested once. At one exercise day from every athlete the iron metabolism especially the change of hepcidin, prohepcidin and iron before and after a specific dragonboat intervention is analysed.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • athletes performing dragon boat sport

Exclusion Criteria:

  • acute clinically significant intercurrent diseases
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01431118

Sponsors and Collaborators
University of Giessen
MVZ für Laboratoriumsmedizin Koblenz
Deutscher Drachenboot Verband e.V.
Investigators
Principal Investigator: Andree Hillebrecht, Dr. med. Department of sportsmedicine- University Giessen
  More Information

No publications provided

Responsible Party: Andree Hillebrecht, Dr.med., University of Giessen
ClinicalTrials.gov Identifier: NCT01431118     History of Changes
Other Study ID Numbers: Gi-02-2011
Study First Received: August 31, 2011
Last Updated: July 21, 2012
Health Authority: Germany: Ethics Commission

Keywords provided by University of Giessen:
iron metabolism
hepcidin
dragon boating
sport-specific stress
iron
anaemia
sport

Additional relevant MeSH terms:
Anemia
Hematologic Diseases

ClinicalTrials.gov processed this record on August 21, 2014