Internet-based Cognitive Behavior Therapy (CBT) for Obsessive Compulsive Disorder (OCD)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified May 2011 by Karolinska Institutet.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
Karolinska Institutet
ClinicalTrials.gov Identifier:
NCT01347099
First received: May 2, 2011
Last updated: May 3, 2011
Last verified: May 2011
  Purpose

Cognitive behavior therapy (CBT) is an effective treatment for obsessive compulsive disorder (OCD) but there is a lack of properly trained CBT therapists. One possible treatment alternative is Internet-based CBT (ICBT) with minimal therapist input. The aim of this study was therefore to evaluate ICBT for OCD.


Condition Intervention Phase
Obsessive Compulsive Disorder
Behavioral: Internet-based cognitive behavior therapy
Behavioral: Support therapy on Internet
Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Internet-based Cognitive Behavior Therapy for Obsessive Compulsive Disorder: A Randomized Controlled Trial

Resource links provided by NLM:


Further study details as provided by Karolinska Institutet:

Primary Outcome Measures:
  • Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment. [ Time Frame: Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended ] [ Designated as safety issue: No ]
    Yale Brown Obsessive Compulsive Scale (Y‐BOCS)


Secondary Outcome Measures:
  • Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment. [ Time Frame: Two days before treatment, once per week for 10 weeks after treatment starts, 3 and 12 months after treatment has ended ] [ Designated as safety issue: No ]
    Obsessive Compulsive Scale - Revised (OCI-R)

  • Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment. [ Time Frame: Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after the treatment has ended ] [ Designated as safety issue: No ]
    Dimensional Obsessive Compulsive Scale (DOCS)

  • Change from Baseline of depressive symptoms after 10 weeks and at 3- and 12 months after treatment. [ Time Frame: Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended ] [ Designated as safety issue: No ]
    Montgomery Asberg Depression Rating Scale

  • Change from Baseline of meta cognitions after 10 weeks and at 3- and 12 months after treatment. [ Time Frame: Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended ] [ Designated as safety issue: No ]
    Obsessive Beliefs Scale

  • Change from Baseline of quality of life after 10 weeks and at 3- and 12 months after treatment. [ Time Frame: Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended ] [ Designated as safety issue: No ]
    Euroqol


Enrollment: 101
Study Start Date: February 2011
Estimated Primary Completion Date: June 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Internet CBT
Internet-delivered CBT. Contact with therapist thru an e-mail system. 10 weeks.
Behavioral: Internet-based cognitive behavior therapy
Internet-delivered CBT. Contact with therapist thru an e-mail system. 10 weeks
Placebo Comparator: Support therapy
10 weeks. Therapist support contact through e-mail.
Behavioral: Support therapy on Internet
Internet-delivered support therapy. Contact with therapist thru an e-mail system. 10 weeks

Detailed Description:

This is a randomized controlled trial with 101 participants. The control group receives support therapy on demand on the Internet.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Primary diagnosis of obsessive compulsive disorder (OCD)
  • At least 18 years old
  • Able to read and write in swedish
  • Computer access

Exclusion Criteria:

  • other primary diagnosis
  • substance abuse,
  • psychosis,
  • bipolar disorder,
  • suicidal ideation,
  • adjusted pharmacological treatment the last two months
  • current psychological treatment for OCD,
  • been treated with CBT the last two years,
  • serious somatic disease,
  • Y--‐BOCS>31
  • hoarding as primary OCD subtype
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01347099

Locations
Sweden
Psykiatri Sydväst
Stockholm, Sweden
Sponsors and Collaborators
Karolinska Institutet
Investigators
Principal Investigator: Christian Rück, MD, PhD Department of Clinical Neuroscience, KI
  More Information

No publications provided

Responsible Party: Nils Lindefors, Psykiatri Sydväst
ClinicalTrials.gov Identifier: NCT01347099     History of Changes
Other Study ID Numbers: OCD-S
Study First Received: May 2, 2011
Last Updated: May 3, 2011
Health Authority: Sweden: Regional Ethical Review Board

Keywords provided by Karolinska Institutet:
CBT
OCD
Internet
Reduce symptom burden

Additional relevant MeSH terms:
Obsessive-Compulsive Disorder
Compulsive Personality Disorder
Anxiety Disorders
Mental Disorders
Personality Disorders

ClinicalTrials.gov processed this record on April 16, 2014