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High-speed Power Training in Older Adults With Knee Osteoarthritis (OA)

This study has been completed.
Sponsor:
Collaborators:
American College of Rheumatology
Arthritis Foundation
Information provided by:
University of Missouri-Columbia
ClinicalTrials.gov Identifier:
NCT01328340
First received: March 31, 2011
Last updated: April 1, 2011
Last verified: March 2011
History of Changes
  Purpose

We are exploring a unique weight-training program for men and women 55 years or older with knee osteoarthritis (OA) that emphasizes high-speed movmenents. We believe that the speed at which muscles move may be more important to the improvement of muscle performance, function and pain than how strong the muscles are. We are comparing high-speed power training with traditional strength training to determine which method has the greatest effects on muscle strength, muscle power, speed of movement, functional performance and pain. We believe that high-speed training will improve these measures to a greater extent than simply training for increased muscle strength.


Condition Intervention
Knee Osteoarthritis
 Other: weight training

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Double Blind (Subject, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: The Effect of High-speed Power Training on Muscle Performance, Function and Pain in Older Adults With Knee OA

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University of Missouri-Columbia:

Primary Outcome Measures:
  • Strength and power [ Time Frame: 3 months ] [ Designated as safety issue: Yes ]
    The strength of the lower limb muscles will be measures using Keiser pneumatic leg press and knee extension exercise machines. The Keiser machines allow for the specific measurement of the contributions of force and velocity to the development of power, which will reveal whether the high-speed training protocol impacts speed-related measures of muscle performance.


Secondary Outcome Measures:
  • Function [ Time Frame: 3 months ] [ Designated as safety issue: Yes ]
    Measures of mobility and function were evaluated using the 400-m Walk, Berg Balance Scale and timed chair rise which assess walking endurance, balance, and stregnth, respectively, all important variables for mobility


Enrollment: 48
Study Start Date: June 2005
Study Completion Date: May 2008
Primary Completion Date: May 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: High-speed power training
Volunteers randomized into SHPT will be exercised 3 times per week for 12 weeks. Each training session will consist of 3 sets of 12 to 14 repetitions at 40% of maximal strength for leg press (LP) and seated knee extension (KE) exercises.
 Other: weight training
Weight training performed 3 times a week for 12 weeks
Active Comparator: Slow-speed strength training
Volunteers randomized into STR will be exercised 3 times per week for 12 weeks. Each training session will consist of 3 sets of 8 to 10 repetitions at 80% of maximal strength for LP and KE exercises.
 Other: weight training
Weight training performed 3 times a week for 12 weeks
No Intervention: Control
Volunteers randomized into CON will undergo a placebo exercise intervention consisting of lower extremity range of motion and flexibility exercises performed 2 times per week with the assistance of the research staff.

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  Eligibility

Ages Eligible for Study:   55 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • 55 years of age
  • physician diagnosed knee OA
  • relatively inactive
  • male or female
  • good overall health
  • living independently (not in a nursing home or care facility)

Exclusion Criteria:

  • heart attack or unstable angina within 6 months of consent
  • hip fracture, knee or hip replacement within 6 months of consent
  • diagnosed neurological disease
  • pulmonary disease requiring use of oxygen
  • osteoarthritis of the knee
  • severe visual or hearing impairment
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01328340

Locations
United States, Missouri
University of Missouri
Columbia, Missouri, United States, 65211
Sponsors and Collaborators
University of Missouri-Columbia
American College of Rheumatology
Arthritis Foundation
  More Information

No publications provided by University of Missouri-Columbia

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Responsible Party: Stephen P. Sayers, University of Missouri
ClinicalTrials.gov Identifier: NCT01328340     History of Changes
Other Study ID Numbers: 1043138
Study First Received: March 31, 2011
Last Updated: April 1, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by University of Missouri-Columbia:
muscle power, exercise, aging

Additional relevant MeSH terms:
Osteoarthritis
Osteoarthritis, Knee
Arthritis
 Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases

ClinicalTrials.gov processed this record on June 18, 2013