Lower Urinary Tract Dysfunction Database

This study is currently recruiting participants. (see Contacts and Locations)
Verified April 2014 by Balgrist University Hospital
Sponsor:
Information provided by (Responsible Party):
Thomas M Kessler, Balgrist University Hospital
ClinicalTrials.gov Identifier:
NCT01293110
First received: February 9, 2011
Last updated: April 25, 2014
Last verified: April 2014
  Purpose

Patients with neurological disease/injury often suffer from lower urinary tract symptoms, which frequently have a negative impact on the patients' health related quality of life. The prevalence of lower urinary tract dysfunction is high and the treatment is a challenge because available treatments may fail. In this study data of patients with lower urinary tract dysfunction treated at the University of Zürich, are prospectively and systematically collected in a database.


Condition
Neurogenic Bladder
Diseases of the Lower Urinary Tract: General Conditions

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Database of Patients With Lower Urinary Tract Dysfunction Treated at the University of Zürich

Resource links provided by NLM:


Further study details as provided by Balgrist University Hospital:

Primary Outcome Measures:
  • Survival of the patients [ Time Frame: first visit to death ] [ Designated as safety issue: No ]

Estimated Enrollment: 3000
Study Start Date: January 2010
Estimated Study Completion Date: January 2016
Estimated Primary Completion Date: January 2016 (Final data collection date for primary outcome measure)
Detailed Description:

Lower urinary tract dysfunction is characterized by detrusor overactivity, detrusor sphincter dyssynergia, voiding dysfunction, stress incontinence, or a combination of these and frequently has a negative impact on the patients' health related quality of life. In addition, the treatment of lower urinary tract dysfunction is a challenge because conventional therapies may fail. Adequate treatment and long-term follow-up of lower urinary tract dysfunction is important to achieve/maintain continence and preserve renal function. Thus, we aim to prospectively collect clinical, video-urodynamic and radiological data of patients with neurogenic lower urinary tract dysfunction treated at the University of Zürich in a database.

  Eligibility

Ages Eligible for Study:   18 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Ages Eligibility: minimum 18 years Genders Eligibility: female and male

Criteria

Inclusion Criteria:

  • patient of Balgrist University Hospital
  • patient of University Hospital Zürich
  • urodynamic examination
  • written informed consent

Exclusion Criteria:

  • no written informed consent
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01293110

Contacts
Contact: Thomas M Kessler, MD +41 44 3863845 thomas.kessler@balgrist.ch
Contact: Dorothee Birnböck, MD +41 44 3863721 dbirnboeck@paralab.balgrist.ch

Locations
Switzerland
Spinal Cord Injury Center & Research, University of Zürich, Balgrist University Hospital Recruiting
Zürich, Switzerland, 8008
Contact: Thomas M Kessler, MD    +41 (44) 386 3845    thomas.kessler@balgrist.ch   
Sponsors and Collaborators
Balgrist University Hospital
  More Information

No publications provided

Responsible Party: Thomas M Kessler, executive physician, Balgrist University Hospital
ClinicalTrials.gov Identifier: NCT01293110     History of Changes
Other Study ID Numbers: EK 2010-0207/0
Study First Received: February 9, 2011
Last Updated: April 25, 2014
Health Authority: Switzerland: Ethikkommission

Keywords provided by Balgrist University Hospital:
urodynamics
neurogenic lower urinary tract dysfunction
neurological disease/injury

Additional relevant MeSH terms:
Urinary Bladder, Neurogenic
Nervous System Diseases
Neurologic Manifestations
Signs and Symptoms
Urinary Bladder Diseases
Urologic Diseases

ClinicalTrials.gov processed this record on October 29, 2014