Effect of Ambient Light on the Parameters of the Pupillary Light Reflex
The purpose of this study is to determine the effects of varying luminescent levels on the pupillary response.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Effect of Ambient Light on the Parameters of the Pupillary Light Reflex|
- pupillary light reflex: amplitude, latency, maximum constriction velocity, mean constriction velocity and dilation velocity during different levels of ambient light [ Time Frame: Pupillometry readings will be taken at 3 potential light readings low light, intermediate light and high ambient light. A total of 48 readings will be done. All parameters will be done at one sitting and will take approximately 45 minutes to complete. ] [ Designated as safety issue: No ]
|Study Start Date:||September 2009|
|Study Completion Date:||February 2010|
|Primary Completion Date:||February 2010 (Final data collection date for primary outcome measure)|
no condition - healthy volunteers
Pupillometry readings will be taken at low, intermediate and high ambient light
Evaluation of the pupillary response is an underemphasized aspect of the assessment of visual function. The pupillary light reflex is one of the few objective indicators of afferent input from the retina and optic nerve. Since the pupillary light reflex is processed through the retina, it may be used to assess visual integrity (1). Pupillometry is a reliable technology capable of providing repetitive data on quantitative pupillary function in states of health and disease (2). Amplitude, latency, maximum constriction velocity, mean constriction velocity, and dilation velocity are measured using the Neuroleptics pupillometer. The effects of varying levels of ambient light on these parameters of the pupillary response have not been extensively studied. The purpose of this investigation is to determine the effects of varying luminescent levels on the pupillary response.
|United States, New Jersey|
|Newark, New Jersey, United States, 07101|
|Principal Investigator:||Lawrence W Chinn, MD||UMDNJ-NJMS|