Baerveldt Plate Area Comparison (BPAC)

• Visual Acuity [ Time Frame: Annual follow-up visits ] [ Designated as safety issue: No ]
  Visual acuity is an important outcome variable in the BPAC. Visual acuity is measured before pupil dilation, tonometry, gonioscopy, or any other technique that could affect vision. Two different techniques are used to measure visual acuity, including Snellen and ETDRS visual acuity testing. Visual acuity is measured at the Qualifying Assessment and at every follow-up visit. ETDRS visual acuity is required at the Qualifying Assessment and at the 1 year, 3 year, and 5 year follow-up visits
  
  

Inclusion criteria (must have all of the following):

1. Age over 18 Y N
2. IOP > 18 mm Hg and < 40 mm Hg on medical therapy Y N
3. Previous ocular surgery limited to cataract, corneal transplant, trabeculectomy, vitrectomy Y N
4. Consent signed Y N

Exclusion criteria (cannot have any of the following):

1. Unwilling or unable to give consent, unwilling to accept randomization, or unable to Y N return for scheduled protocol visits
2. Pregnant or nursing Y N
3. NLP vision Y N
4. Iris neovascularization or proliferative retinopathy Y N
5. Iridocorneal endothelial syndrome Y N
6. Epithelial or fibrous downgrowth Y N
7. Chronic or recurrent uveitis Y N
8. Steroid-induced glaucoma Y N
9. Severe posterior blepharitis Y N
10. Previous cyclodestructive procedure Y N
11. Conjunctival scarring from prior ocular trauma or cicatrizing disease (e.g. Stevens Johnson syndrome, ocular pemphigoid) precluding Baerveldt implantation. Y N
12. Functionally significant cataract Y N
13. Need for Baerveldt implant combined with other ocular procedures (ie cataract surgery, Y N penetrating keratoplasty, or retinal surgery) or anticipated need for additional ocular surgery
14. Prior glaucoma drainage device (tube) implant Y N
15. Prior retinal surgery with remaining silicone oil Y N
16. Prior scleral buckling procedures