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Exercise and Cognitive Training in Parkinson's Disease

This study is currently recruiting participants.
Verified February 2013 by Department of Veterans Affairs
Sponsor:
Collaborator:
University of Maryland
Information provided by (Responsible Party):
Department of Veterans Affairs
ClinicalTrials.gov Identifier:
NCT01156714
First received: March 11, 2010
Last updated: February 6, 2013
Last verified: February 2013
History of Changes
  Purpose

This study looks at whether treadmill exercise and memory training on a computer can improve memory in Parkinson's Disease


Condition Intervention
Parkinson's Disease
 Behavioral: treadmill training
Behavioral: computerized memory training

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Effects of Exercise and Cognitive Training on Executive Function in Parkinson's Disease

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Department of Veterans Affairs:

Primary Outcome Measures:
  • Improved executive function on a neuropsychological test battery [ Time Frame: 3 months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Improved dual task ability [ Time Frame: 3 months ] [ Designated as safety issue: No ]
  • Improvement in instrumental activities of daily living [ Time Frame: 3 months ] [ Designated as safety issue: No ]

Estimated Enrollment: 121
Study Start Date: October 2010
Estimated Study Completion Date: July 2014
Estimated Primary Completion Date: December 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Arm 1
Treadmill training with aerobic exercise
 Behavioral: treadmill training
walk on treadmill for aerobic exercise
Arm 2
Memory training with computerized memory program
 Behavioral: computerized memory training
memory testing and training on computer program
Arm 3
Combination of treadmill training and computerized memory program
 Behavioral: treadmill training
walk on treadmill for aerobic exercise
Behavioral: computerized memory training
memory testing and training on computer program

Detailed Description:

Executive memory loss is common in Parkinson's Disease (PD). There is no known treatment for it. This study looks at whether executive memory function is improved in PD by either treadmill aerobic training, computerized memory training, or a combination of both.

  Eligibility

Ages Eligible for Study:   40 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Parkinson's disease stage 1-3 Hoehn and Yahr
  • Balance problems

Exclusion Criteria:

  • unstable medical illness
  • unstable psychiatric illness
  • exercising too much on own
  • doing computerized memory training on own
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01156714

Contacts
Contact: Terra Hill (410) 328-5800 thill@som.umaryland.edu
Contact: Alexander Loreck, BS (410) 605-7000 ext 4858 alexander.loreck@va.gov

Locations
United States, Maryland
Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD Recruiting
Baltimore, Maryland, United States, 21201
Contact: Terra Hill     410-328-5800     thill@som.umaryland.edu    
Principal Investigator: Karen E Anderson, MD            
Sponsors and Collaborators
Department of Veterans Affairs
University of Maryland
Investigators
Principal Investigator: Karen E Anderson, MD VA Maryland Health Care System, Baltimore
  More Information

No publications provided

Responsible Party: Department of Veterans Affairs
ClinicalTrials.gov Identifier: NCT01156714     History of Changes
Other Study ID Numbers: E7158-R
Study First Received: March 11, 2010
Last Updated: February 6, 2013
Health Authority: United States: Federal Government

Keywords provided by Department of Veterans Affairs:
Parkinson's disease
Treadmill training
Exercise
 Cognitive Training
executive function
dual task

Additional relevant MeSH terms:
Parkinson Disease
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
 Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases

ClinicalTrials.gov processed this record on May 16, 2013