SPECT/CT in the Diagnosis of Dementia (DEMSPET)

This study has been completed.
Sponsor:
Collaborator:
University of Eastern Finland
Information provided by:
Kuopio University Hospital
ClinicalTrials.gov Identifier:
NCT01112501
First received: April 27, 2010
Last updated: NA
Last verified: April 2010
History: No changes posted
  Purpose

Aim of the study is to evaluate whether Tc-99m-ECD-SPECT/CT enhances early diagnosis of dementia in two specific patient groups: (1) patient with mild cognitive impairment, and (2) patient with possible symptoms and signs of frontotemporal dementia. Evaluation of SPECT/CT data is performed both by visual and quantitative voxel-based analyses (Statistical Parametric Mapping). The final diagnosis is based on up to four years clinical follow-up.


Condition
Dementia

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: SPECT/CT in the Diagnosis of Dementia

Resource links provided by NLM:


Further study details as provided by Kuopio University Hospital:

Primary Outcome Measures:
  • Final diagnosis [ Time Frame: 4 years ] [ Designated as safety issue: No ]
    (1) controls, (2) stable mild cognitive impairment (MCI), (3)MCI converted to Alzheimers's disease (AD), (4) frontotemporal dementia (FTD), suspected FTD converted to AD, (5) other final diagnoses


Enrollment: 82
Study Start Date: September 2006
Study Completion Date: January 2010
Primary Completion Date: January 2010 (Final data collection date for primary outcome measure)
  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

Subjects with possible/suspected early dementia

Criteria

Inclusion Criteria (one of these):

  • healthy control
  • mild cognitive impairment (recruited from a population based data)
  • clinically suspected frontotemporal dementia (unset diagnosis)

Exclusion Criteria:

  • unable to be scanned with SPECT/CT
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01112501

Locations
Finland
Kuopio University Hospital
Kuopio, Finland, 70211
Sponsors and Collaborators
Kuopio University Hospital
University of Eastern Finland
  More Information

No publications provided

Responsible Party: Esko Vanninen / Professor, Kuopio University Hospital
ClinicalTrials.gov Identifier: NCT01112501     History of Changes
Other Study ID Numbers: KUH5031339
Study First Received: April 27, 2010
Last Updated: April 27, 2010
Health Authority: Finland: Research Ethics Committee, Hospital District of Northern Savo, Finland

Keywords provided by Kuopio University Hospital:
Diagnosis
Dementia
Imaging

Additional relevant MeSH terms:
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders

ClinicalTrials.gov processed this record on August 20, 2014