The Effects of Joint Effusion on Proprioception
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Purpose
The purpose of this study is to assess the effects of joint effusion on proprioceptive status in patients with knee osteoarthritis (OA).
| Condition | Intervention |
|---|---|
|
Osteoarthritis |
Procedure: Normal saline |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single Blind (Investigator) |
| Official Title: | Clinical Trial for the Effects of Joint Effusion on Proprioception |
- Proprioceptive acuity in Knee Joint. Proprioceptive acuity (difference between the knee angles at the target and reproduced positions) was assessed by active repositioning of the lower limb after injection or no injection. [ Time Frame: within one hour after intervention ] [ Designated as safety issue: No ]
| Enrollment: | 40 |
| Study Start Date: | May 2009 |
| Study Completion Date: | January 2010 |
| Primary Completion Date: | January 2010 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Active Comparator: Infusion
20cc saline infusion into the knee joint
|
Procedure: Normal saline
20 cc normal saline injection into the knee joint
Other Name: Normal saline
|
| No Intervention: No infusion |
Procedure: Normal saline
20 cc normal saline injection into the knee joint
Other Name: Normal saline
|
Detailed Description:
Proprioception is a sensory modality that provides feedback on the internal status of the body and enables us to perceive joint position and motion.
Osteoarthritis (OA), also called degenerative joint disease, is a major musculoskeletal condition characterized by loss of articular cartilage that leads to pain and loss of function. The most commonly affected joint is the knee, and OA may result in changes that affect not only intracapsular tissues, but also periarticular tissues, such as ligaments, capsules, tendons, and muscles. Many studies have examined the proprioceptive status of knee OA, and subjects with knee OA are known to have impaired proprioception compared with age-matched controls.
Joint effusion is a common symptom associated with chronic degenerative joint condition, but the effects of effusion on knee joint proprioception have not been investigated in detail.
A volume of 20 mL of normal saline was injected into the knee joint cavity of subjects in the experimental group under ultrasonographic guidance. Proprioceptive acuity was assessed by active repositioning of the lower limb using an electrogoniometer to measure knee joint position sense (JPS) under both non-weight-bearing and weight-bearing conditions twice, with a 20-min rest interval.
Eligibility| Ages Eligible for Study: | 50 Years and older |
| Genders Eligible for Study: | Female |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Or at least two of criteria 2-6 established by the American College of Rheumatology (ACR):
- Kellgren and Lawrence (K/L) grade ≥II
- morning stiffness <30 min in duration
- crepitus on movement of the knee joint
- bony tenderness at the knee joint margins
- palpable or visible bony enlargement
- no palpable warmth.
Exclusion Criteria:
- the presence of knee joint effusion determined by ultrasonography
- a history of knee injury or surgery
- a history of knee injection within 3 months
- a history of inflammatory arthritis
- taking anticoagulants
- balance or gait disturbance
- diabetes mellitus.
Contacts and Locations| Korea, Republic of | |
| Seoul St. Mary's Hospital | |
| Seoul, Korea, Republic of, 137-701 | |
| Study Chair: | Jongin Lee, M.D | Department of Rehabilitation Medicine, Seoul St. Mary's Hospital |
More Information
Additional Information:
No publications provided by The Catholic University of Korea
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
| Responsible Party: | JongIn Lee/Department of Rehabilitation Medicine,, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea |
| ClinicalTrials.gov Identifier: | NCT01060215 History of Changes |
| Other Study ID Numbers: | 52008B000100044 |
| Study First Received: | January 28, 2010 |
| Last Updated: | February 1, 2010 |
| Health Authority: | Korea: Institutional Review Board |
Keywords provided by The Catholic University of Korea:
|
effusion osteoarthritis knee |
Additional relevant MeSH terms:
|
Osteoarthritis Hydrarthrosis Arthritis |
Joint Diseases Musculoskeletal Diseases Rheumatic Diseases |
ClinicalTrials.gov processed this record on May 21, 2013