Physiological Investigations of Movement Disorders
This study is currently recruiting participants.
Verified January 2013 by National Institutes of Health Clinical Center (CC)
Information provided by:
National Institutes of Health Clinical Center (CC)
First received: November 24, 2009
Last updated: August 6, 2013
Last verified: January 2013
Show Detailed Description
- Previous studies have given researchers information on how the brain controls movement, how people learn to make fine, skilled movements, and why some people have movement disorders. However, further research is needed to learn more about the causes of most movement disorders, such as Parkinson's disease.
- By using small, specialized studies to evaluate people with movement disorders and compare them with healthy volunteers, researchers hope to learn more about the changes in the brain and possible causes of movement disorders.
- To better understand how the brain controls movement.
- To learn more about movement disorders.
- To train movement disorder specialists.
- Individuals 18 years of age or older who have had a movement disorder diagnosed by a neurologist and are able to participate based on the specific requirements of the small study.
- Healthy volunteers 18 years of age or older.
- Participants will have a screening visit with medical history, physical examination, and questionnaire to determine eligibility. Eligible participants will give consent to participate in up to seven additional outpatient visits for study procedures. The number of sessions and the procedures needed for participation depend on specific symptoms.
- Participants must avoid drinking alcohol or caffeinated drinks (sodas, coffee, and tea) for at least 2 days (48 hours) before each session.
- Potential studies may include magnetic resonance imaging (MRI) scans, functional MRI scans, electroencephalography, magnetoencephalography, transcranial magnetic stimulation, nerve and sensory stimulation, or movement and mental tasks during any of the above procedures.
- This study does not provide treatment for movement disorders. Participants will not have to stop any treatment in order to participate.
|Study Design:||Time Perspective: Prospective|
|Official Title:||Physiological Investigations of Movement Disorders|
Resource links provided by NLM:
Genetics Home Reference related topics: dopa-responsive dystonia early-onset primary dystonia Parkinson disease Perry syndrome sepiapterin reductase deficiency Tourette syndrome
MedlinePlus related topics: Dystonia MRI Scans Movement Disorders Parkinson's Disease Tourette SyndromeU.S. FDA Resources
Further study details as provided by National Institutes of Health Clinical Center (CC):
Primary Outcome Measures:
- MRI Signals, EEG/MEG signals, Ampitude of muscle potentials (MEP) evocked by TMS.
|Study Start Date:||October 2009|
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01019343
|Contact: Elaine P Considine, R.N.||(301) firstname.lastname@example.org|
|Contact: Mark Hallett, M.D.||(301) email@example.com|
|United States, Maryland|
|National Institutes of Health Clinical Center, 9000 Rockville Pike||Recruiting|
|Bethesda, Maryland, United States, 20892|
|Contact: For more information at the NIH Clinical Center contact Patient Recruitment and Public Liaison Office (PRPL) 800-411-1222 ext TTY8664111010 firstname.lastname@example.org|
Sponsors and Collaborators
|Principal Investigator:||Mark Hallett, M.D.||National Institute of Neurological Disorders and Stroke (NINDS)|