Pilot Study of Text Message Reminders to Improve HIV Medication Adherence in Botswana

This study has been completed.
Sponsor:
Information provided by:
University of Pennsylvania
ClinicalTrials.gov Identifier:
NCT01001741
First received: October 23, 2009
Last updated: February 18, 2011
Last verified: June 2010
  Purpose

While medication adherence is critical to successful treatment of HIV, there are few studies of interventions demonstrating improvements in adherence. This may be a particular challenge in the developing world, which has a larger burden of HIV but fewer resources than industrialized countries. The investigators propose a randomized controlled trial of cellular phone text message reminders to improve medication adherence. Our pilot study will be set in a large HIV clinic in Gaborone, Botswana, where Penn researchers have collaborated on research projects in the past. The primary study outcome will be antiretroviral medication adherence.


Condition Intervention
HIV Infections
Other: Cell phone text message

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Supportive Care
Official Title: A Pilot Study of Cellular Phone Text Message Reminders to Improve HIV Medication Adherence at Independence Surgery Clinic Gaborone, Botswana

Resource links provided by NLM:


Further study details as provided by University of Pennsylvania:

Primary Outcome Measures:
  • HIV medication adherence [ Time Frame: Monthly ] [ Designated as safety issue: No ]

Estimated Enrollment: 128
Study Start Date: June 2008
Study Completion Date: August 2009
Primary Completion Date: August 2009 (Final data collection date for primary outcome measure)
Intervention Details:
    Other: Cell phone text message
    We will use cellular text messages to remind patients of impending drug prescription refills and scheduled visits to their healthcare provider.
  Eligibility

Ages Eligible for Study:   21 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • HIV infected
  • 21 years of age or older

Exclusion Criteria:

  • Subjects who do not intend to have continuous follow-up care and monthly medication refills at Independence Surgery for at least the next six months
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01001741

Locations
Botswana
Independence Surgery
Gaborone, Botswana
Sponsors and Collaborators
University of Pennsylvania
Investigators
Study Director: Darren Linkin, MD University of Pennsylvania
Principal Investigator: Harvey Friedman, MD University of Pennsylvania
Study Director: James Thompson, MBA Wharton Business School, UPenn
Study Director: Andrew Steenhoff University of Pennsylvania
  More Information

No publications provided

Responsible Party: Ian C. MacMillan, Wharton Entrepreneurial Programs, Wharton School, UPenn
ClinicalTrials.gov Identifier: NCT01001741     History of Changes
Other Study ID Numbers: 805891, NIH: P30 AI 045008
Study First Received: October 23, 2009
Last Updated: February 18, 2011
Health Authority: United States: Institutional Review Board
Botswana: Ministry of Health

Keywords provided by University of Pennsylvania:
HIV
Antiretrovirals
Adherence
Text messaging
Antiretroviral adherence
Treatment experienced

Additional relevant MeSH terms:
Acquired Immunodeficiency Syndrome
HIV Infections
Immune System Diseases
Immunologic Deficiency Syndromes
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Sexually Transmitted Diseases
Sexually Transmitted Diseases, Viral
Slow Virus Diseases
Virus Diseases

ClinicalTrials.gov processed this record on October 29, 2014