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S-100B and Neuron-specific Enolase (NSE) in Spinal Trauma (WBS)

This study has been completed.
Sponsor:
Information provided by:
Medical University of Vienna
ClinicalTrials.gov Identifier:
NCT00980434
First received: September 18, 2009
Last updated: April 3, 2012
Last verified: July 2011
  Purpose

The investigators are studying the clinical worth of the serum markers S-100B and NSE in patients with spinal cord injuries e.g. in patients with vertebral fractures. If there is a injury to the neuronal structures these two proteins could be secreted into the serum and add evidence to the severity of the injury.


Condition
Spinal Cord Injury

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Clinical Use of S-100B and NSE in Spinal Cord Injuries

Resource links provided by NLM:


Further study details as provided by Medical University of Vienna:

Primary Outcome Measures:
  • Neurological Symptoms [ Time Frame: 2 weeks ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples Without DNA

Serum probe


Enrollment: 60
Study Start Date: February 2008
Study Completion Date: December 2011
Primary Completion Date: November 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
patients with neurological symptoms
2
patients without neurological symptoms

  Eligibility

Ages Eligible for Study:   1 Year and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

patients from daily practice

Criteria

Inclusion Criteria:

  • vertebral fracture
  • injuries to the vertebral spine

Exclusion Criteria:

  • head trauma
  • polytrauma
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00980434

Locations
Austria
Medical University of Vienna
Vienna, Austria, 1090
Sponsors and Collaborators
Medical University of Vienna
Investigators
Study Chair: Vilmos Vecsei, M.D. Professor Head of Department
  More Information

Publications:
Responsible Party: Wolf Harald Dr., Department for Trauma Surgery
ClinicalTrials.gov Identifier: NCT00980434     History of Changes
Other Study ID Numbers: Wolf-4
Study First Received: September 18, 2009
Last Updated: April 3, 2012
Health Authority: Austria : Federal Ministry for Labour, Health, and Social Affairs

Keywords provided by Medical University of Vienna:
vertebral fracture
spinal cord injury

Additional relevant MeSH terms:
Spinal Cord Injuries
Central Nervous System Diseases
Nervous System Diseases
Spinal Cord Diseases
Trauma, Nervous System
Wounds and Injuries

ClinicalTrials.gov processed this record on November 25, 2014