Bone Marrow and Blood Samples From Patients With Metastatic Choroid Melanoma
RATIONALE: Studying samples of bone marrow and blood from patients with cancer may help doctors find out the extent of disease.
PURPOSE: This research study is collecting bone marrow and blood samples from patients with metastatic choroid melanoma.
Genetic: gene expression analysis
Genetic: reverse transcriptase-polymerase chain reaction
Other: laboratory biomarker analysis
|Official Title:||Evaluation of the Detection of Tumor Cells in Bone Marrow and Blood in Patients With Choroid Melanoma|
- Detection of micro-metastatic cells in 20 x 10^6 nucleated cells [ Designated as safety issue: No ]
|Study Start Date:||November 2007|
|Primary Completion Date:||May 2011 (Final data collection date for primary outcome measure)|
- Develop and validate a method of detecting tumor cells in the bone marrow and blood in patients with metastatic choroid melanoma.
OUTLINE: While patients are under general anesthesia for standard treatment of their disease, samples of bone marrow from the iliac crest and blood are collected. Samples are analyzed for the expression of tyrosinase and Melan-a via RT-PCR.