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Examination of B Cell Responses in Human Blood

The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2008 by Regenerative Medicine Network.
Recruitment status was  Active, not recruiting
Sponsor:
Collaborator:
University of Leipzig
Information provided by:
Regenerative Medicine Network
ClinicalTrials.gov Identifier:
NCT00806845
First received: December 10, 2008
Last updated: March 11, 2009
Last verified: December 2008
  Purpose

The aim of this study is the assessment B-cell immune responses in HIV-infected individuals.


Condition
HIV Infections

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Gewinnung Humaner antikörperproduzierender Zellen Aus Dem Blut

Resource links provided by NLM:


Further study details as provided by Regenerative Medicine Network:

Primary Outcome Measures:
  • Antigen specific B-cell responses [ Time Frame: 18 months ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples Without DNA

peripheral blood


Estimated Enrollment: 40
Study Start Date: July 2008
Estimated Study Completion Date: May 2011
Estimated Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts
HIV infected individuals
HIV infected individuals with or without AIDS
Control
HIV negative individuals

Detailed Description:

Groups of patients with different immune competencies will be examined. The impact of HIV infection on immune response will be assessed.

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

HIV patients and controls attending specialised clinics, Germany

Criteria

Inclusion Criteria:

  • HIV-infected individuals
  • controls

Exclusion Criteria:

- none

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00806845

Locations
Germany
Universität Leipzig
Leipzig, Sachsen, Germany, 04103
Sponsors and Collaborators
Regenerative Medicine Network
University of Leipzig
Investigators
Study Director: Christian Jassoy, MD Universität Leipzig
  More Information

No publications provided

Responsible Party: Christian Jassoy MD, Universität Leipzig
ClinicalTrials.gov Identifier: NCT00806845     History of Changes
Other Study ID Numbers: RegMedNet-001
Study First Received: December 10, 2008
Last Updated: March 11, 2009
Health Authority: Germany: Ethics Commission

Keywords provided by Regenerative Medicine Network:
HIV
B-lymphocyte

Additional relevant MeSH terms:
Acquired Immunodeficiency Syndrome
HIV Infections
Immune System Diseases
Immunologic Deficiency Syndromes
Lentivirus Infections
RNA Virus Infections
Retroviridae Infections
Sexually Transmitted Diseases
Sexually Transmitted Diseases, Viral
Slow Virus Diseases
Virus Diseases

ClinicalTrials.gov processed this record on November 20, 2014