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| Sponsor: | Argentine Tennis Association |
|---|---|
| Information provided by: | Argentine Tennis Association |
| ClinicalTrials.gov Identifier: | NCT00792376 |
Purpose
The purpose of this study is to evaluate etoricoxib efficacy in pain control, leg stiffness and functional recovery of patients suffering acute Achilles tendinopathy.
It is hypothesized that etoricoxib (120mg orally/day/7 days) efficacy is not inferior to diclofenac (150mg orally /day/7 days) for pain control in subjects suffering acute Achilles tendinopathy.
| Condition | Intervention | Phase |
|---|---|---|
|
Achilles Tendinopathy |
Drug: etoricoxib Drug: diclofenac |
Phase IV |
| Study Type: | Interventional |
| Study Design: | Treatment, Randomized, Double Blind (Subject, Investigator, Outcomes Assessor), Active Control, Parallel Assignment, Efficacy Study |
| Official Title: | "NSAIDs in Acute Achilles Tendinopathy: Effect on Pain Control, Leg Stiffness and Functional Recovery in Athletes" |
| Estimated Enrollment: | 56 |
| Study Start Date: | January 2009 |
| Estimated Study Completion Date: | April 2010 |
| Estimated Primary Completion Date: | December 2009 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
etoricoxib: Experimental
etoricoxib (ETO) group (n=28) treated with etoricoxib 120 mg/day orally for 7 days
|
Drug: etoricoxib
etoricoxib (ETO) group (n=28) treated with etoricoxib 120 mg/day orally for 7 days
Drug: diclofenac
diclofenac (DIC) group (n=28) received diclofenac 150 mg/day/7 days orally.
|
|
diclofenac: Active Comparator
diclofenac (DIC) group (n=28) received diclofenac 150 mg/day/7 days orally.
|
Drug: diclofenac
diclofenac (DIC) group (n=28) received diclofenac 150 mg/day/7 days orally.
|
Eligibility| Ages Eligible for Study: | 18 Years to 50 Years |
| Genders Eligible for Study: | Male |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Javier Maquirriain, MD | 54 9 11 4478 8367 | jmaquirriain@yahoo.com |
| Contact: Vanesa Vinciunas | 54 9 341 5855555 | vanuvin@yahoo.com.ar |
| Argentina | |
| Argentine Tennis Association | |
| Buenos Aires, Argentina | |
More Information
| Responsible Party: | Argentine Tennis Association ( Javier Maquirriain MD, PhD ) |
| Study ID Numbers: | 00045-2008, 1-47-12225-05-1 |
| Study First Received: | November 14, 2008 |
| Last Updated: | November 14, 2008 |
| ClinicalTrials.gov Identifier: | NCT00792376 History of Changes |
| Health Authority: | Argentina: Administracion Nacional de Medicamentos, Alimentos y Tecnologia Medica |
|
NSAID tendon pain stiffness Achilles |
|
Anti-Inflammatory Agents Tendon Injuries Molecular Mechanisms of Pharmacological Action Cyclooxygenase Inhibitors Physiological Effects of Drugs Etoricoxib Wounds and Injuries Disorders of Environmental Origin Diclofenac Enzyme Inhibitors Pharmacologic Actions |
Tendinopathy Muscular Diseases Musculoskeletal Diseases Analgesics, Non-Narcotic Sensory System Agents Therapeutic Uses Anti-Inflammatory Agents, Non-Steroidal Analgesics Peripheral Nervous System Agents Antirheumatic Agents Central Nervous System Agents |