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A Survey to Evaluate the Rate of Abnormal Glucose Tolerance Among Hong Kong Chinese Subjects With Coronary Heart Disease

This study has suspended participant recruitment.
Sponsor:
Information provided by:
Chinese University of Hong Kong
ClinicalTrials.gov Identifier:
NCT00786175
First received: November 5, 2008
Last updated: October 15, 2010
Last verified: October 2010
  Purpose

Hypothesis: there is a high prevalence rate of diabetes, including asymptomatic undiagnosed glucose intolerance, among subjects with coronary heart disease in Hong Kong.

A cross-sectional survey is planned to study the rate of undiagnosed diabetes and glucose intolerance among the Chinese patients with coronary heart disease in Hong Kong. The survey results will be important for us to plan the logistics to investigate and manage the potential glucose abnormality of our heart disease patient.


Condition
Coronary Heart Disease
Diabetes Mellitus

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: A Cross-sectional Observational Survey to Evaluate the Rate of Diabetes and Glucose Intolerance (Both Diagnosed and Undiagnosed) Among Hong Kong Chinese Subjects With Coronary Heart Disease

Resource links provided by NLM:


Further study details as provided by Chinese University of Hong Kong:

Estimated Enrollment: 3000
Study Start Date: October 2008
Estimated Study Completion Date: January 2014
Estimated Primary Completion Date: September 2013 (Final data collection date for primary outcome measure)
Detailed Description:

Diabetes is becoming an epidemic in Hong Kong, affecting over 10% of population and causing a major burden to the health care system. Over 30-40% of patients admitted to the medical wards of the Hospital Authority hospitals have diabetes as a contributory factor. It was estimated that thirty to fifty percent of patients with stroke, heart failure or acute myocardial infarction have diabetes as a key causative factor. However, the exact prevalence rate of diabetes, including asymptomatic undiagnosed glucose intolerance, among subjects with coronary heart disease is still unknown in Hong Kong. Many heart disease patients with undiagnosed diabetes remained being untreated on their abnormal glycemic status, which will further aggravate the heart disease and impair the prognosis.

The investigators plan to conduct a cross-sectional survey to study the rate of undiagnosed diabetes and glucose intolerance among the Chinese patients with coronary heart disease in Hong Kong. The survey results will be important for us to plan the logistics to investigate and manage the potential glucose abnormality of our heart disease patient.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Hong Kong Chinese with history of coronary heart disease being diagnosed in 2008 in HA hospitals

Criteria

Inclusion Criteria:

  1. Patients aged 18 years
  2. Subjects admitted to Hospital Authority hospital as in-patients (AHNH) with the diagnosis of coronary heart disease (ICD code 410-414) during the period 1 April 2007 to 31 March 2008.
  3. Subjects admitted to AHNH for the procedure Percutaneous Coronary Intervention (PCI) to manage coronary heart disease.

Exclusion Criteria:

  1. Known Type 1 diabetes defined as history of ketosis [acute symptoms with heavy ketonuria (>3+) or ketoacidosis] or heavy ketonuria (3+) or continuous requirement of insulin treatment within one year of diagnosis and thereafter.
  2. Patients with terminal malignancy or other life-threatening diseases with less than 6-month expected survival
  3. Patients with a mental condition rendering the subject unable to understand the nature, scope, and possible consequences of the study
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00786175

Locations
China
Hong Kong Institute of Diabetes and Obesity
Hong Kong, China
Sponsors and Collaborators
Chinese University of Hong Kong
Investigators
Principal Investigator: Gary Ko, MD Asia Diabetes Foundation
  More Information

No publications provided

Responsible Party: Gary Ko, Hong Kong Institute of Diabetes and Obesity
ClinicalTrials.gov Identifier: NCT00786175     History of Changes
Other Study ID Numbers: CRE-2008.336
Study First Received: November 5, 2008
Last Updated: October 15, 2010
Health Authority: Hong Kong: Ethics Committee

Additional relevant MeSH terms:
Coronary Artery Disease
Coronary Disease
Diabetes Mellitus
Heart Diseases
Myocardial Ischemia
Arterial Occlusive Diseases
Arteriosclerosis
Cardiovascular Diseases
Endocrine System Diseases
Glucose Metabolism Disorders
Metabolic Diseases
Vascular Diseases

ClinicalTrials.gov processed this record on November 27, 2014