Middle and Inner Ear Malformation in Children With Velocardiofacial Syndrome
Middle and inner ear malformations on two boys with velocardiofacial syndrome are discussed.Special attention should be given to the presence of hearing loss due to middle and inner ear malformations, in addition to frequent conductive hearing loss regarding mastoid and middle ear inflammatory processes.
Ear Malformations in the Velocardiofacial Syndrome
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Middle and Inner Ear Malformation in Children With Velocardiofacial Syndrome|
|Study Start Date:||January 2007|
|Study Completion Date:||June 2007|
|Primary Completion Date:||March 2007 (Final data collection date for primary outcome measure)|
Two boys with clinical signs of velocardiofacial syndrome, at ages of 4.7 and 6,7 years old are the subjects of this study.Audiological evaluation, including pure tone audiometry, tympanometry, acoustical reflex, and Computerized Tomography of temporal bones, and analyses of DNA sample with markers of 22q11 region were performed.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00784173
|Principal Investigator:||Alfredo Tabith-Junior, MD||Pontificia Universidade Católica de São Paulo|