Adventure: Teacher Delivered Personality-targeted Interventions for Substance Misuse - Full Text View

Purpose

Several personality factors have been shown to be associated with risk for alcohol and substance misuse, and differentiate substance abusers based on clinical profile, treatment response and susceptibility to other forms of mental illness. Personality-targeted interventions have been found to have significant preventative effects on onset and growth of drinking, binge-drinking and drinking problems in adolescents attending mainstream schools (Conrod, Castellanos & Mackie, 2008). The interventions concurrently reduced personality-specific emotional and behavioural problems (Castellanos & Conrod, 2006), and prevented the onset and escalation of drug-use over a two-year period (Conrod, Castellanos-Ryan & Strang, 2010). This cluster randomised controlled trial aims to examine whether these results can be replicated when interventions are delivered by trained educational professionals. In addition, the trial will evaluate the broader impact of the programme on cigarette smoking, school attendance, academic achievement and school-wide behaviours.

Condition	Intervention	Phase
Alcohol Abuse Drug Abuse Depression Panic Disorder Conduct Disorder	Behavioral: Personality-targeted interventions	Phase 2 Phase 3

Study Type:	Interventional
Study Design:	Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Factorial Assignment Masking: Open Label Primary Purpose: Prevention
Official Title:	Cognitive Behavioral Interventions That Target Personality Risk for Substance Abuse and Mental Illness: Delivery by Educational Professionals

Resource links provided by NLM:

MedlinePlus related topics: Anxiety Child Mental Health Depression Mental Disorders Panic Disorder

U.S. FDA Resources

Further study details as provided by King's College London:

Primary Outcome Measures:

Binge drinking frequency [ Time Frame: 2 years ] [ Designated as safety issue: No ]
Frequency in the past 6 months that subject reported drinking 5 or more alcoholic beverages (4 or more for girls) on one drinking occasion.
Drinking frequency [ Time Frame: 2 years ] [ Designated as safety issue: No ]
Past six months frequency of drinking
drinking quantity [ Time Frame: 2 years ] [ Designated as safety issue: No ]
Average number of alcoholic beverages consumed on a typical drinking occasion in the past six months
Drinking problems [ Time Frame: 2 years ] [ Designated as safety issue: No ]
number of drinking problems reported on an abbreviated version of the Rutger's Alcohol Problem Index.
illicit drug use events [ Time Frame: 2 years ] [ Designated as safety issue: No ]
Time to onset of illicit drug use

Secondary Outcome Measures:

Emotional and behavioural problems, targeted and school-wide effects [ Time Frame: 2 years ] [ Designated as safety issue: No ]
Psychiatric symptoms (depression, panic anxiety, antisocial behaviours), coping skills, motives for drinking, school attendance and attainment, in-class behaviours assessed using the Strengths and Difficulties Questionnaire and the Brief Symptom Inventory.

Enrollment:	3190
Study Start Date:	May 2007
Study Completion Date:	May 2010
Primary Completion Date:	March 2010 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Experimental: learning to cope with your impulsivity Cognitive-behavioural intervention targeting impulsive personality	Behavioral: Personality-targeted interventions Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained teacher and co-facilitator Other Name: Preventure, but now delivered by teachers
Experimental: learning to cope with your sensation seeking cognitive behavioural intervention designed to help sensation seeking youth manage their need for stimulation and excitement.	Behavioral: Personality-targeted interventions Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained teacher and co-facilitator Other Name: Preventure, but now delivered by teachers
Experimental: learning to cope with your anxiety sensitivity cognitive behavioural intervention teaching anxiety sensitive youth to manager their sensitivity to threat and anxiety.	Behavioral: Personality-targeted interventions Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained teacher and co-facilitator Other Name: Preventure, but now delivered by teachers
Experimental: learning to manage your negative thinking cognitive behavioural intervention targeting pessimistic and negative thinking in hopeless youth	Behavioral: Personality-targeted interventions Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained teacher and co-facilitator Other Name: Preventure, but now delivered by teachers

Detailed Description:

The Adventure study aims to examine whether educational professionals such as teachers, mentors or individuals in a pastoral role, who are trained in carrying out personality-targeted interventions will be effective in reducing problem behaviours in a group of adolescents.

20 schools in London, U.K. were recruited for the trial, and over 2000 adolescents (mean age 13.7 years) consented to participate in the survey and intervention phases of the trial. Schools were randomly assigned to control or intervention condition, and students in intervention schools who met the criteria for any of the 4 personality risk subscales of the Substance Use Risk Profile Scale (Negative Thinking, Anxiety Sensitivity, Sensation Seeking and Impulsivity) were invited to participate in a personality-targeted intervention by trained members of staff from their schools. All participants were invited to complete follow-up surveys at 6-month intervals for 2 years. The remaining 55% of low risk students in the grad were also followed to examine population-level effects of the intervention as well.

The main outcome measures of this RCT are alcohol and illicit drug outcomes. Secondary measures include mental health symptoms, risky behaviour, school attainment and attendance, and school-wide behaviours.

It is hypothesised that teacher-delivered personality-targeted interventions will have similar preventative effects on alcohol and drug use as reported by Conrod et al (2008, 2010), in addition to the personality-specific intervention effects reported by Castellanos & Conrod (2006). In addition, broader effects of the intervention on academic achievement and school-wide behaviour will be examined in this trial, both at the individual level and at the population-level.

Eligibility

Ages Eligible for Study:	13 Years to 16 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Secondary school student

Exclusion Criteria:

None

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00776685

Locations

United Kingdom
Institute of Psychiatry, King's College London
London, United Kingdom

Sponsors and Collaborators

King's College London

Action on Addiction

Investigators

Study Chair:

Patricia J Conrod, PhD

King's College London

More Information

Publications:

O'Leary-Barrett M, Mackie CJ, Castellanos-Ryan N, Al-Khudhairy N, Conrod PJ. Personality-targeted interventions delay uptake of drinking and decrease risk of alcohol-related problems when delivered by teachers. J Am Acad Child Adolesc Psychiatry. 2010 Sep;49(9):954-963.e1. Epub 2010 Jul 31.

Conrod PJ, Castellanos-Ryan N, Strang J. Brief, personality-targeted coping skills interventions and survival as a non-drug user over a 2-year period during adolescence. Arch Gen Psychiatry. 2010 Jan;67(1):85-93.

Conrod PJ, Castellanos N, Mackie C. Personality-targeted interventions delay the growth of adolescent drinking and binge drinking. J Child Psychol Psychiatry. 2008 Feb;49(2):181-90.

Conrod PJ, Stewart SH, Comeau N, Maclean AM. Efficacy of cognitive-behavioral interventions targeting personality risk factors for youth alcohol misuse. J Clin Child Adolesc Psychol. 2006 Dec;35(4):550-63.

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Conrod PJ, O'Leary-Barrett M, Newton N, Topper L, Castellanos-Ryan N, Mackie C, Girard A. Effectiveness of a selective, personality-targeted prevention program for adolescent alcohol use and misuse: a cluster randomized controlled trial. JAMA Psychiatry. 2013 Mar;70(3):334-42. doi: 10.1001/jamapsychiatry.2013.651.

Responsible Party:	Dr. Patricia Conrod, Institute of Psychiatry, King's College London
ClinicalTrials.gov Identifier:	NCT00776685 History of Changes
Other Study ID Numbers:	Adventure
Study First Received:	October 17, 2008
Last Updated:	June 24, 2011
Health Authority:	United Kingdom: Research Ethics Committee

Additional relevant MeSH terms:

Depression
Depressive Disorder
Substance-Related Disorders
Panic Disorder
Alcoholism
Conduct Disorder
Behavioral Symptoms

Mood Disorders
Mental Disorders
Anxiety Disorders
Alcohol-Related Disorders
Attention Deficit and Disruptive Behavior Disorders
Mental Disorders Diagnosed in Childhood

ClinicalTrials.gov processed this record on May 16, 2013