Ventricular Remodeling In Patients With Aortic Stenosis Assessed Echocardiography
This preliminary study will compare the effectiveness of two-dimensional and three-dimensional echocardiographic measurements of wall thickness and left ventricular mass in patients with Aortic Stenosis
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Patterns Of Left Ventricular Remodeling In Patients With Aortic Stenosis Assessed By Two-Dimensional And Three-Dimensional Echocardiography|
- Evaluate 2-dimensional and 3-dimensional echocardiography for LV patterns of remodeling and hypertrophy [ Time Frame: 1 hour ] [ Designated as safety issue: No ]
- Assess doppler diastolic filling indices for patterns of LV remodeling [ Time Frame: 1 hour ] [ Designated as safety issue: No ]
|Study Start Date:||September 2008|
|Study Completion Date:||February 2012|
|Primary Completion Date:||February 2012 (Final data collection date for primary outcome measure)|
This study will evaluate left ventricular patterns of remodeling and hypertrophy in patients with aortic stenosis, and compare two-dimensional echocardiography measurements (wall thickness) with three-dimensional echocardiography data(left ventricular mass). Along with a second objective to assess Doppler diastolic filling indices associated with the various patterns of left ventricular remodeling.
Previous studies(see reference list) were primarily derived from two-dimensional echo data set(based on wall thickness). Various patterns of left ventricular remodeling have been described in response to increased pressure overload.
Three-dimensional echocardiography is a relatively new technique that is being increasingly used in the Echocardiography Lab in selected patients. This technique holds promise of being more accurate for volume-related measurements than the standard 2-dimensional echocardiography techniques.
|United States, Massachusetts|
|Lahey Clinic, Inc.|
|Burlington, Massachusetts, United States, 01805|
|Principal Investigator:||Sherif B. Labib, M.D.||Lahey Clinic, Inc.|