Left Ventricular Lead Position in Cardiac Resynchronization Therapy
Left ventricular (LV) lead position has crucial impact on cardiac resynchronization therapy (CRT) success. This study will compare fluoroscopy and myocardial deformation imaging for optimal definition of LV lead position.
Procedure: Implantation of a cardiac resynchronization therapy device
Procedure: Echocardiography (myocardial deformation imaging)
|Study Design:||Time Perspective: Retrospective|
|Official Title:||Optimal Definition of Left Ventricular Lead Position in Cardiac Resynchronization Therapy by Myocardial Deformation Imaging|
- Improvement in LV function and LV remodelling [ Time Frame: 6 to 12 months ] [ Designated as safety issue: No ]
heart failure patients undergoing CRT implantation
|Procedure: Implantation of a cardiac resynchronization therapy device Procedure: Echocardiography (myocardial deformation imaging)|
In a 16 segment model circumferential strain will be used to determine the segment with latest peak systolic circumferential strain prior to CRT, considered as the optimal LV lead target. LV lead will be defined by (1) fluoroscopy, (2) the maximal temporal difference of peak circumferential strain before-to-on CRT and (3) the earliest peak systolic circumferential strain during LV pacing. For all 3 modalities optimal LV lead position is defined as concordance or immediate neighbouring of the segment with defined LV lead position to the determined optimal target segment. At follow-up echocardiography will be performed to determine improvement in LV function and remodeling.
|Department of Cardiology, RWTH Aachen University Hospital|
|Aachen, Germany, 52057|
|Principal Investigator:||Michael Becker, MD||RWTH Aachen University Hospital|
|Study Chair:||Rainer Hoffmann, MD||RWTH Aachen University Hospital|