Effects of Cognitive Intervention for Older Adults With Memory Decline: A Pilot Study - Full Text View

Sponsor:	McGill University Health Center
Information provided by:	McGill University Health Center
ClinicalTrials.gov Identifier:	NCT00609427

Purpose

The purpose of this study is to evaluate the effects of training in memory skills vs. use of external memory aids on everyday memory functioning in older people with mild cognitive impairment.

Condition	Intervention	Phase
Mild Cognitive Impairment	Behavioral: MEMO programme (Inst Universitaire de Geriatrie, Montreal) Behavioral: External memory aids training	Phase I

Study Type:	Interventional
Study Design:	Treatment, Randomized, Double Blind (Investigator, Outcomes Assessor), Parallel Assignment, Efficacy Study
Official Title:	Effects of Cognitive Intervention for Older Adults With Memory Decline: A Pilot Study

Resource links provided by NLM:

MedlinePlus related topics: Memory

U.S. FDA Resources

Further study details as provided by McGill University Health Center:

Primary Outcome Measures:

Rey Auditory Verbal Learning Test [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
Wechsler Memory Scale - Logical Memory [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
Face-name associations test [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
Multifactorial Memory Questionnaire - Ability subscale [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

Rivermead Behavioural Memory Test [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
FAS test (non-memory) [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
Category fluency (non-memory test) [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
Victoria Stroop Test (non-memory test) [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
Digit Span (non-memory test) [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
Multifactorial Memory Questionnaire - Strategies and Contentment subscales [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]

Estimated Enrollment:	30
Study Start Date:	August 2008
Estimated Study Completion Date:	June 2010
Estimated Primary Completion Date:	December 2009 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
EA: Experimental Training in external memory aids	Behavioral: External memory aids training 8 weekly group sessions of training in the use of external memory aids, administered by clinical psychologist
MT: Experimental Mnemonic training intervention	Behavioral: MEMO programme (Inst Universitaire de Geriatrie, Montreal) 8 weekly group training sessions in mnemonic strategies, administered by clinical psychologist.
WL: No Intervention Wait-list control

Detailed Description:

Some older people experience memory loss that is worse than other people of their age, although they are not demented. This condition is known as mild cognitive impairment (MCI). Healthy older people can learn mnemonic strategies to improve their memory abilities. Can cognitive rehabilitation help people with MCI do better on mental tasks or maintain better functioning in everyday life? This study will evaluate the effects of two different rehabilitation programmes. Patients in the memory training group will learn mental strategies aimed at improving memory. Patients in the memory compensation group will learn to use external memory aids.

Eligibility

Ages Eligible for Study:	65 Years to 90 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Clinical diagnosis of mild cognitive impairment

Exclusion Criteria:

Unable to speak and understand English
Unable to comply with treatment program due to significant comorbid illness; OR
Anticipated inability to attend all study sessions

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00609427

Contacts

Contact: Haiqun Xie, Medical

514-934-1934 ext 34420

xhqhr2@hotmail.com

Locations

Canada, Quebec
McGill University Health Centre	Recruiting
Montreal, Quebec, Canada, H3A 1A1
Contact: Lisa Koski (514) 843-5704 lisa.koski@mcgill.ca
Contact: Lisa Koski (514) 843-5704 lisa.koski@mcgill.ca
Sub-Investigator: Guylaine Bachand Bachand, RN
Sub-Investigator: Gary Inglis, MD
Sub-Investigator: Yves Bacher, MD
Sub-Investigator: Sue Pietrantonio, RN
Sub-Investigator: Alyson Turner, RN
Sub-Investigator: Joelle Crane, PhD

Sponsors and Collaborators

McGill University Health Center

Investigators

Principal Investigator:

Lisa Koski, PhD

Research Institute of the McGill University Health Centre

More Information

No publications provided

Responsible Party:	Research Institute of the McGill University Health Centre ( Lisa Koski )
Study ID Numbers:	BMB08, BMB08
Study First Received:	January 24, 2008
Last Updated:	February 16, 2009
ClinicalTrials.gov Identifier:	NCT00609427 History of Changes
Health Authority:	Canada: Ethics Review Committee

Keywords provided by McGill University Health Center:

cognitive training
cognitive rehabilitation

Additional relevant MeSH terms:

Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders
Cognition Disorders

ClinicalTrials.gov processed this record on November 09, 2009