Optical Coherence Tomography of Airway and Pleural Disorders
Endobronchial disorders represent abnormal processes within the network of passages delivering air to the lung, including lung cancers. Pleural disorders involve the membrane that covers the lung and lines the inside of the chest walls.
Early detection of these disorders is essential to timely, accurate diagnosis and treatment of these conditions including cancer, inflammation and infections.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Optical Coherence Tomography of Airway and Pleural Disorders|
- Screening aid in identification of suspect tissue lesion. [ Time Frame: 30 MINUTES ] [ Designated as safety issue: No ]
|Study Start Date:||July 2007|
|Estimated Study Completion Date:||July 2015|
|Estimated Primary Completion Date:||July 2015 (Final data collection date for primary outcome measure)|
Optical methods for obtaining images in airway passages for early detection of endobronchial lung and pleural cancer are needed. Optical coherence tomography (OCT) is a non-invasive or minimally invasive diagnostic technique that can provide information about tissue abnormalities.
OCT can produce images of abnormalities both at and below the surface of the airways without damaging the tissue surface This technique uses a harmless device to emit infrared (not visible) light that can produce images of the specimen under investigation without causing damage or alterations.
|United States, California|
|Beckman Laser Institute, UCI|
|Irvine, California, United States, 92612|
|Pulmonary and Critecal Care Medicine, UCI Medical Center|
|Orange, California, United States, 92868|
|Principal Investigator:||Matthew Brenner, M.D||Beckman Laser Institute|