Effects of Exercise Modality on Abdominal Obesity and Health Risk Factors in Older Men and Women

This study has been completed.
Sponsor:
Collaborator:
Canadian Institutes of Health Research (CIHR)
Information provided by:
Queen's University
ClinicalTrials.gov Identifier:
NCT00520858
First received: August 24, 2007
Last updated: April 21, 2008
Last verified: April 2008
  Purpose

The prevalence of abdominal obesity in the elderly is increasing at alarming rates and thus, requires immediate attention. By comparison to younger adults, obesity reduction in the elderly presents a unique challenge and requires an innovative approach. We propose a novel approach to investigate the effects of different exercise types as independent treatment strategies for the reduction of obesity and related health risk factors in older men and women. We propose that exercise without caloric restriction will be associated with modest weight loss (3-5%), that in turn will be associated with significant reduction in abdominal obesity, insulin resistance, and a corresponding increase in skeletal muscle mass and function. We will determine the separate effects of resistance and aerobic exercise on these primary outcome variables, and, whether a treatment strategy that combines the two is optimal.


Condition Intervention
Abdominal Obesity
Other: Resistance Exercise (RE)
Other: Aerobic Exercise (AE)
Other: Resistance and Aerobic Exercise (RAE)

Study Type: Interventional
Study Design: Intervention Model: Parallel Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Treatment
Official Title: Effects of Exercise Modality on Abdominal Obesity and Health Risk Factors in Older Men and Women

Resource links provided by NLM:


Further study details as provided by Queen's University:

Primary Outcome Measures:
  • Abdominal obesity [ Time Frame: 6 months ]

Secondary Outcome Measures:
  • Insulin Resistance [ Time Frame: 6 Months ]

Enrollment: 145
Study Start Date: September 2003
Arms Assigned Interventions
No Intervention: C
Active Comparator: RE
Resistance Exercise
Other: Resistance Exercise (RE)
Active Comparator: AE
Aerobic Exercise
Other: Aerobic Exercise (AE)
Active Comparator: RAE
Resistance and Aerobic
Other: Resistance and Aerobic Exercise (RAE)

  Eligibility

Ages Eligible for Study:   65 Years to 80 Years
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • Men and women between 65 and 80 years of age.
  • Men and women are self-sufficient, sedentary, abdominally obese (BMI between 27 and 34.9 kg/m2; waist circumference greater than 88 cm in women and 102 cm in men), weight stable (± 2 kg) for 6 months prior to the beginning of the study, be non-smokers, and not diabetic.
  • We will study elderly women who are not taking hormone replacement therapy to create a homogeneous population in whom the effect of exercise on the principal outcome variables can be evaluated with minimal confounding.

Exclusion Criteria:

  • Smokers and diabetics.
  • Women taking hormone replacement therapy.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00520858

Locations
Canada, Ontario
Queen's University
Kingston, Ontario, Canada, K7L 3N6
Sponsors and Collaborators
Queen's University
Canadian Institutes of Health Research (CIHR)
Investigators
Principal Investigator: Robert Ross Queen's University
  More Information

No publications provided by Queen's University

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00520858     History of Changes
Other Study ID Numbers: Ross2002
Study First Received: August 24, 2007
Last Updated: April 21, 2008
Health Authority: Canada: Canadian Institutes of Health Research

Additional relevant MeSH terms:
Obesity
Obesity, Abdominal
Overnutrition
Nutrition Disorders
Overweight
Body Weight
Signs and Symptoms

ClinicalTrials.gov processed this record on July 23, 2014