Furosemide Inhalation in Dyspnea of Mustard Gas Exposed Patients

This study has been completed.

First Received: August 7, 2007 No Changes Posted

Sponsor:	Baqiyatallah Medical Sciences University
Information provided by:	Baqiyatallah Medical Sciences University
ClinicalTrials.gov Identifier:	NCT00512811

Purpose

to assess the efficacy of inhaled furosemide in mustard gas exposed patients with acute respiratory failure

Condition	Intervention	Phase
Bronchiolitis	Drug: furosemide	Phase III

Study Type:	Interventional
Study Design:	Supportive Care, Randomized, Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Crossover Assignment
Official Title:	Furosemide Inhalation in Dyspnea of Mustard Gas Exposed Patients: a Double-Blind Randomized Study

Resource links provided by NLM:

MedlinePlus related topics: Breathing Problems Gas

Drug Information available for: Mechlorethamine Furosemide Mechlorethamine hydrochloride Mustard gas

U.S. FDA Resources

Further study details as provided by Baqiyatallah Medical Sciences University:

Primary Outcome Measures:

effect of furosemid inhalation on dyspnea

Eligibility

Ages Eligible for Study:	32 Years to 83 Years
Genders Eligible for Study:	Male

Criteria

Inclusion Criteria:

Patients with a history of exposure to sulfur mustard with a complaint of dyspnea

Exclusion Criteria:

A contraindication for furosemide use;
An accompanying disease in which other drugs effective for dyspnea were used

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00512811

Locations

Iran, Islamic Republic of
RCCI
Tehran, Iran, Islamic Republic of

Sponsors and Collaborators

Baqiyatallah Medical Sciences University

Investigators

Study Chair:

Mostafa Ghanei, MD

Research Center of Chemical Injuries, Baqiyatallah Medical Science University, Tehran, Iran

More Information

No publications provided

Study ID Numbers:	121a25
Study First Received:	August 7, 2007
Last Updated:	August 7, 2007
ClinicalTrials.gov Identifier:	NCT00512811 History of Changes
Health Authority:	Iran: Ethics Committee

Keywords provided by Baqiyatallah Medical Sciences University:

furosemide
inhalation
dyspnea
spirometry

mustard gas
bronchiolitis
sulfur mustard

Additional relevant MeSH terms:

Molecular Mechanisms of Pharmacological Action
Bronchial Diseases
Bronchiolitis
Physiological Effects of Drugs
Diuretics
Respiration Disorders
Cardiovascular Agents
Furosemide
Pharmacologic Actions
Membrane Transport Modulators
Signs and Symptoms
Mustard Gas

Lung Diseases, Obstructive
Respiratory Tract Diseases
Respiratory Tract Infections
Natriuretic Agents
Therapeutic Uses
Lung Diseases
Signs and Symptoms, Respiratory
Bronchitis
Sodium Potassium Chloride Symporter Inhibitors
Dermatologic Agents
Dyspnea

ClinicalTrials.gov processed this record on February 08, 2010