Hemodynamic Changes After Aortic Aneurysm Treatment With Stent-Graft

This study is currently recruiting participants.

Verified by University of California, San Francisco, January 2008

First Received: June 18, 2007 Last Updated: May 2, 2008 History of Changes

Sponsor:	University of California, San Francisco
Information provided by:	University of California, San Francisco
ClinicalTrials.gov Identifier:	NCT00488358

Purpose

To compare the aortic pulse profile before and after stent-graft implantation to prove that endovascular AAA repair using non-compliant stent-graft changes the aortic pulse profile.

Condition
Abdominal Aortic Aneurysm

Study Type:	Observational
Study Design:	Case-Only, Prospective
Official Title:	Hemodynamic Changes After Aortic Aneurysm Treatment With Stent-Graft

Resource links provided by NLM:

MedlinePlus related topics: Aneurysms Aortic Aneurysm

U.S. FDA Resources

Further study details as provided by University of California, San Francisco:

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	10
Study Start Date:	November 2005
Estimated Primary Completion Date:	January 2009 (Final data collection date for primary outcome measure)

Detailed Description:

This study will assess hemodynamic changes in aortas of patients after treatment of their abdominal aortic aneurysm (AAA) with an FDA approved stent-graft (Zenith). This study does not require any change in clinical protocol to the the way the AAA procedures are currently done. Utilizing the catheters already employed in this procedure, intravascular blood pressure measurements will be documented at various times and at various anatomic levels prior to and after deployment of the stent-graft.

As the compliant aortic aneurysm acts as a capacitor, expanding during systole and contracting during diastole, it is our hypothesis that endovascular AAA repair using a non-compliant stent-graft changes the aortic pulse profile.

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

Patients with Abdominal Aortic Aneurysm with planned treatment using Zenith Endovascular Stent-Graft

Criteria

Inclusion Criteria:

Abdominal Aortic Aneurysm with planned treatment using Zenith Endovascular Stent-Graft

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00488358

Contacts

Contact: Jade S Hiramoto, MD

415 353 4366

hiramotoj@surgery.ucsf.edu

Locations

United States, California
Division of Vascular Surgery, UCSF	Recruiting
San Francisco, California, United States, 94143

Sponsors and Collaborators

University of California, San Francisco

Investigators

Principal Investigator:

Jade S Hiramoto, MD

Assistant Professor in Residence

More Information

No publications provided

Responsible Party:	UCSF ( Jade S. Hiramoto, MD )
Study ID Numbers:	H51821-27504
Study First Received:	June 18, 2007
Last Updated:	May 2, 2008
ClinicalTrials.gov Identifier:	NCT00488358 History of Changes
Health Authority:	United States: Institutional Review Board

Keywords provided by University of California, San Francisco:

abdominal
aortic
aneurysm
Zenith
blood pressure

Additional relevant MeSH terms:

Aortic Diseases
Aneurysm
Aortic Aneurysm, Abdominal

Vascular Diseases
Cardiovascular Diseases
Aortic Aneurysm

ClinicalTrials.gov processed this record on February 08, 2010