Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS

This study has been completed.
Sponsor:
Information provided by:
Ziv Hospital
ClinicalTrials.gov Identifier:
NCT00466050
First received: April 25, 2007
Last updated: August 23, 2009
Last verified: April 2007
  Purpose

Thirty patients scheduled to coronary angiography and IVUS in according to their treating physician decision will be enrolled in the study. The coronary angiography and IVUS will be done on according to regular clinical standards.

As the study protocol, 40 cc of blood will be drawn from the patients after written informed consent.

The laboratory tests will be processed for the above mentioned serum markers of unstable plaque.

A multivariate correlation test will be done between the different serum markers and the plaque morphology by angiography and composition (virtual histology) by IVUS.


Condition
Acute Coronary Thrombose
Plaque Rupture
Acute Coronary Syndrome

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS

Further study details as provided by Ziv Hospital:

Estimated Enrollment: 30
Study Start Date: April 2007
Study Completion Date: May 2009
Primary Completion Date: April 2008 (Final data collection date for primary outcome measure)
  Show Detailed Description

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Patients scheduled to coronary angiography and IVUS

Criteria

Inclusion Criteria:

  • Both genders: males and females
  • Age - above 18 years
  • Patients scheduled to coronary angiography and IVUS
  • Written Informed Consent Form

Exclusion Criteria:

  • Pregnant or breast-feeding woman
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00466050

Locations
Israel
Heart Institute ,Ziv Medical Center
Safed, Israel, 13110
Sponsors and Collaborators
Ziv Hospital
Investigators
Principal Investigator: Osamah Hussein, MD Ziv Medical Center
Principal Investigator: Alon Marmor, Prof Ziv Medical Center
  More Information

Publications:

Responsible Party: Ziv Hospital
ClinicalTrials.gov Identifier: NCT00466050     History of Changes
Other Study ID Numbers: HP-7-234-S
Study First Received: April 25, 2007
Last Updated: August 23, 2009
Health Authority: Israel: Ministry of Health

Keywords provided by Ziv Hospital:
plaque rupture,
acute coronary thrombose,
coronary angiography,
IVUS

Additional relevant MeSH terms:
Acute Coronary Syndrome
Rupture
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Angina Pectoris
Vascular Diseases
Chest Pain
Pain
Signs and Symptoms
Wounds and Injuries

ClinicalTrials.gov processed this record on September 16, 2014