the Comparison Efficacy of Azithromycin With Doxycycline in the Treatment of Acne Vulgaris

This study is currently recruiting participants.

Verified by Shaheed Beheshti Medical University, January 2008

First Received: January 8, 2007 Last Updated: January 28, 2008 History of Changes

Sponsor:	Shaheed Beheshti Medical University
Information provided by:	Shaheed Beheshti Medical University
ClinicalTrials.gov Identifier:	NCT00419848

Purpose

a comparison of efficacy and adverse side effects occurrence of Doxycycline and Azithromycin in the management of moderate acne vulgaris

Condition	Intervention	Phase
Acne	Drug: Doxycycline Drug: Azithromycin	Phase II

Study Type:	Interventional
Study Design:	Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study
Official Title:	the Comparison Efficacy of Azithromycin With Doxycycline in the Treatment of Acne Vulgaris

Resource links provided by NLM:

MedlinePlus related topics: Acne

Drug Information available for: Doxycycline Doxycycline hyclate Azithromycin Doxycycline calcium

Further study details as provided by Shaheed Beheshti Medical University:

Primary Outcome Measures:

change in acne lesions [ Time Frame: 12 weeks ] [ Designated as safety issue: Yes ]

Secondary Outcome Measures:

global response rates, patient's own assessment, side effects and compliance [ Time Frame: 12 weeks ] [ Designated as safety issue: Yes ]

Estimated Enrollment:	100
Study Start Date:	August 2006
Estimated Study Completion Date:	February 2008
Estimated Primary Completion Date:	January 2008 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
1: Experimental	Drug: Azithromycin Azithromycin: Cap 250 mg- 500 mg single dose/daily - 3 times per week
2: Active Comparator	Drug: Doxycycline Cap 100mg- 100mg/daily

Eligibility

Criteria

Inclusion Criteria:

Between 18 to 30 year old
Moderate facial Acne(At least 10 inflammatory lesions with maximum 3 nodules and pseudocysts

Exclusion Criteria:

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00419848

Contacts

Contact: Parviz Toossi, M.D.

98-21-22744393 ext 5

Locations

Iran, Islamic Republic of
Shaheed Beheshti Medical University, Skin research center	Recruiting
Tehran, Iran, Islamic Republic of, 198994148

Sponsors and Collaborators

Shaheed Beheshti Medical University

Investigators

More Information

No publications provided

Responsible Party:	Shaheed Beheshti Medical unversity ( Skin research center )
Study ID Numbers:	src-hmj-1385
Study First Received:	January 8, 2007
Last Updated:	January 28, 2008
ClinicalTrials.gov Identifier:	NCT00419848 History of Changes
Health Authority:	Iran: Ministry of Health

Keywords provided by Shaheed Beheshti Medical University:

Acne
Azithromycin
Doxycycline

Additional relevant MeSH terms:

Anti-Infective Agents
Antiprotozoal Agents
Facial Dermatoses
Skin Diseases
Sebaceous Gland Diseases
Acne Vulgaris
Pharmacologic Actions

Anti-Bacterial Agents
Antimalarials
Antiparasitic Agents
Acneiform Eruptions
Azithromycin
Therapeutic Uses
Doxycycline

ClinicalTrials.gov processed this record on November 27, 2009