Endometrial Sampling (Pipelle)in IVF Patients

The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2006 by Sheba Medical Center.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Sheba Medical Center
ClinicalTrials.gov Identifier:
NCT00411021
First received: December 12, 2006
Last updated: NA
Last verified: December 2006
History: No changes posted
  Purpose

A prospective cross-over randomized study aimed to test the hypothesis that local injury of the endometrium increases the implantation rate in the successive cycle. Seventy IVF patients will be randomly selected to undergo either endometrial biopsies or minimal cervical scratch on days 8-10 and 21-23 of their cycle, preceding the IVF treatment. If not pregnant, the women will continue for another IVF cycle, preceded by endometrial or cervical scratch complimentary to their procedure in the first cycle. The main major outcomes will include pregnancy rate, implantation rate, endometrial thickness, abortion rate, live births and embryo quality.


Condition Intervention
Infertility
Procedure: Pipelle (Endometrial Sampling)

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Single Blind
Primary Purpose: Treatment
Official Title: Endometrial Sampling (Pipelle)in IVF Patients

Resource links provided by NLM:


Further study details as provided by Sheba Medical Center:

Estimated Enrollment: 70
  Eligibility

Ages Eligible for Study:   20 Years to 45 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Women undergoing IVF treatment
  • Repeated Implantation failure

Exclusion Criteria:

  • PID or suspected PID
  • Undiagnosed Irregular Bleeding
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00411021

Contacts
Contact: Micha Baum, MD baumdr@zahav.net.il

Locations
Israel
IVF Unit, Sheba Medical Center Recruiting
Ramat-Gan, Israel, 52621
Contact: Micha Baum, MD       baumdr@zahav.net.il   
Sponsors and Collaborators
Sheba Medical Center
Investigators
Principal Investigator: Micha Baum, MD Sheba Medical Center, Israel
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00411021     History of Changes
Other Study ID Numbers: SHEBA-05-3674-MB-CTIL
Study First Received: December 12, 2006
Last Updated: December 12, 2006
Health Authority: Israel: Israeli Health Ministry Pharmaceutical Administration

Additional relevant MeSH terms:
Infertility
Genital Diseases, Male
Genital Diseases, Female

ClinicalTrials.gov processed this record on July 23, 2014