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Effects of Naproxen on Physical Performance

This study has been terminated.
(Study never initiated.)
Sponsor:
Information provided by:
University of Oklahoma
ClinicalTrials.gov Identifier:
NCT00410995
First received: December 12, 2006
Last updated: October 10, 2007
Last verified: October 2007
History of Changes
  Purpose

The purpose of this study is to determine the effect of daily use of Naproxen (a commonly used over-the-counter NSAID) on the physical performance of athletes, as measured by maximum oxygen consumption.


Condition Intervention Phase
Healthy
 Drug: Naproxen
 Phase 4

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Effects of Naproxen on Physical Performance

Resource links provided by NLM:

MedlinePlus related topics: Oxygen Therapy
U.S. FDA Resources

Further study details as provided by University of Oklahoma:

Primary Outcome Measures:
  • Effects on physical performance in terms of maximum oxygen consumption

Estimated Enrollment: 40
Study Start Date: May 2004
Study Completion Date: August 2006
  Eligibility

Ages Eligible for Study:   18 Years to 30 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  1. Age equal to or greater than18 years of age
  2. No history of allergy or adverse reaction to any NSAID
  3. No use of any NSAID in past 2 weeks
  4. No history of peptic ulcer disease (PUD), gastroesophageal disease (GERD), or gastritis
  5. No major medical history including but not limited to diabetes, hypertension, asthma, kidney disease and coronary artery disease
  6. Currently not taking any medication including oral contraceptives

Exclusion Criteria:

  1. Age < 18 years of age
  2. History of allergy or adverse reaction to any NSAID
  3. Use of any NSAID in past 2 weeks
  4. History of a bleeding disorder
  5. History of PUD, GERD, or gastritis
  6. Pregnant
  7. A medical history of diabetes, hypertension, asthma, kidney disease or coronary artery disease
  8. Taking any medication including oral contraceptives
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00410995

Locations
United States, Oklahoma
Family Practice - CMT
Tulsa, Oklahoma, United States, 74104
Sponsors and Collaborators
University of Oklahoma
Investigators
Principal Investigator: LaMont Cavanagh, MD University of Oklahoma-Tulsa
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00410995     History of Changes
Other Study ID Numbers: 11186
Study First Received: December 12, 2006
Last Updated: October 10, 2007
Health Authority: United States: Institutional Review Board

Keywords provided by University of Oklahoma:
Physically fit volunteers

Additional relevant MeSH terms:
Naproxen
Anti-Inflammatory Agents, Non-Steroidal
Analgesics, Non-Narcotic
Analgesics
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Pharmacologic Actions
 Anti-Inflammatory Agents
Therapeutic Uses
Antirheumatic Agents
Gout Suppressants
Cyclooxygenase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Central Nervous System Agents

ClinicalTrials.gov processed this record on June 18, 2013