Anti Ischemic Effects of Abciximab in Angioplasty and Stenting Patients (AIR)
TITLE: Anti-Ischemic effects of Abciximab(Reopro)
PATIENT POPULATION: Patients undergoing PCI(an interventional procedure placing a small stent/metallic tube to keep a narrowed artery in your heart open) and either on a stable statin dose or not on a statin. Statin= cholesterol lowering drug(ie, lipitor, zocor).
INTERVENTION: Heparin vs. heparin + abciximab during PCI
PURPOSE: Measure the effects of abciximab on special healing blood stem cells (EPC's-Endothelial Progenitor Cells), on inflammation, on oxidative stress and on microvascular blood flow.
- 50ccs blood draw on day 1(from sheath), day 2 ,day 7 and day 28.
- Measurement of blood flow in selected suitable patients
- 10 minute questionnaire before discharge and on visit on day 28.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Anti Ischemic Effects of Abciximab in Angioplasty and Stenting Patients (AIR)|
|United States, Georgia|
|Emory University Hospital|
|Atlanta, Georgia, United States, 30322|
|Atlanta VA Medical Center|
|Atlanta, Georgia, United States, 30033|
|Principal Investigator:||Arshed A Quyyumi, M.D.||EUH|