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| Sponsored by: |
University Hospital, Strasbourg, France |
| Information provided by: | University Hospital, Strasbourg, France |
| ClinicalTrials.gov Identifier: | NCT00372281 |
Purpose
USPIO contrast enhancement results from intracellular trapping of the iron particles in reactive cells, especially macrophages. 17FDG-PET studies have demonstrated that macrophages are present in spine infectious diseases but are absent in spine degenerative diseases. The aim of this work is to compare the enhancement induced by CLIAVIST in both diseases. The absence of macrophages in degenerative lesions should help to differentiate them from infectious lesions, who should present contrast enhancement in relation to the presence of macrophages.
| Condition | Intervention | Phase |
|
Spine Infection |
Drug: Cliavist |
Phase III |
| Study Type: | Interventional |
| Study Design: | Diagnostic, Non-Randomized, Open Label, Active Control, Single Group Assignment, Efficacy Study |
| Official Title: | Comparison of Cliavist Enhancement in Infectious and Degenerative Diseases of the Spine |
Eligibility
| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Jean-Louis Dietemann, MD | jean-louis.dietemann@chru-strasbourg.fr | |
| Contact: Stéphane Kremer, MD | stephane.kremer@chru-strasbourg.fr |
| France | |||||
| Service de Radiologie 2 - Hôpital de Hautepierre | Recruiting | ||||
| Strasbourg, France, 67098 | |||||
| Contact: Jean-louis Dietemann, MD jean-louis.dietemann@chru-strasbourg.fr | |||||
| Contact: Stephane Kremer, MD stephane.kremer@chru-strasbourg.fr | |||||
| Sub-Investigator: Jean-Louis Dietemann, MD | |||||
| Principal Investigator: Stéphane Kremer, MD | |||||
| Service de Rhumatologie - Hôpital de Hautepierre | Not yet recruiting | ||||
| Strasbourg, France, 67098 | |||||
| Contact: Jean Sibilia, MD jean.sibilia@chru-strasbourg.fr | |||||
| Principal Investigator: Jean Sibilia, MD | |||||
| Service de Radiologie B - Hôpital Jean Minjoz | Not yet recruiting | ||||
| Besançon, France, 25030 | |||||
| Contact: Jean-François Bonneville, MD jean-françois.bonneville@ufc-chu.univ-fcomte.fr | |||||
| Contact: Michel Runge, MD michel.runge@ufc-chu.univ-fcomte.fr | |||||
| Principal Investigator: Jean-François Bonneville, MD | |||||
| Sub-Investigator: Michel Runge, MD | |||||
| Service de Neuroradiologie - Hôpital Central | Not yet recruiting | ||||
| Nancy, France, 54035 | |||||
| Contact: Serge Bracard, MD s.bracard@chu-nancy.fr | |||||
| Contact: Emmanuelle Schmitt, MD e.schmitt@chu-nancy.fr | |||||
| Principal Investigator: Serge Bracard, MD | |||||
| Sub-Investigator: Emmanuelle Schmitt, MD | |||||
| University Hospital, Strasbourg, France |
| Study Director: | Jean-Louis Dietemann, MD | Hôpitaux Universitaires de Strasbourg |
More Information
| Study ID Numbers: | 3780 |
| First Received: | September 4, 2006 |
| Last Updated: | March 8, 2007 |
| ClinicalTrials.gov Identifier: | NCT00372281 |
| Health Authority: | France: Ministry of Health |
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