Registry for Acute Decompensated Heart Failure Patients - Full Text View

Sponsored by:	Scios, Inc.
Information provided by:	Scios, Inc.
ClinicalTrials.gov Identifier:	NCT00366639

Purpose

ADHERE® is a multi-center, observational, open-label registry of the management of patients treated in the hospital for acute HF in the United States.

Condition
Heart Failure, Congestive Heart Decompensation

Study Type:	Observational
Study Design:	Retrospective
Official Title:	ADHERE Core III - Acute Decompensated Heart Failure Registry

Resource links provided by NLM:

MedlinePlus related topics: Heart Failure

U.S. FDA Resources

Further study details as provided by Scios, Inc.:

Study Start Date:	October 2001
Estimated Study Completion Date:	February 2006

Detailed Description:

The objective is to compile a clinical database on the medical management of patients hospitalized with acute HF, using information collected from acute care hospitals across the United States; To assist hospitals in evaluating and improving quality of care for patients with acute HF by tracking quality indicators and providing benchmark data reports; To describe the demographic and clinical characteristics of patients who are hospitalized with acute HF; To characterize the initial emergency department evaluation and subsequent inpatient management of patients hospitalized with acute HF; To identify patient characteristics and medical care practices associated with improved health outcomes in those hospitalized with acute HF; To characterize trends and changes over time in the management of acute HF; To offer surveillance of adherence to practice guidelines as these emerge for the inpatient management of acute HF.

N/A

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Age greater than or equal to 18 years at the time of admission to the hospital. Received or is eligible to receive a principal hospital discharge diagnosis of HF
Decompensated HF is present as determined clinically by the patient care team

Exclusion Criteria:

HF is present as a co-morbid condition, but is not a principal focus of diagnosis or treatment during this hospitalization episode

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00366639

Sponsors and Collaborators

Scios, Inc.

Investigators

Study Director:

Scios, Inc. Clinical Trial

Scios, Inc.

More Information

No publications provided by Scios, Inc.

Additional publications automatically indexed to this study by National Clinical Trials Identifier (NCT ID):

Maisel AS, Peacock WF, McMullin N, Jessie R, Fonarow GC, Wynne J, Mills RM. Timing of immunoreactive B-type natriuretic peptide levels and treatment delay in acute decompensated heart failure: an ADHERE (Acute Decompensated Heart Failure National Registry) analysis. J Am Coll Cardiol. 2008 Aug 12;52(7):534-40.

Kamath SA, Drazner MH, Wynne J, Fonarow GC, Yancy CW. Characteristics and outcomes in African American patients with decompensated heart failure. Arch Intern Med. 2008 Jun 9;168(11):1152-8.

Peacock WF 4th, De Marco T, Fonarow GC, Diercks D, Wynne J, Apple FS, Wu AH; ADHERE Investigators. Cardiac troponin and outcome in acute heart failure. N Engl J Med. 2008 May 15;358(20):2117-26.

Fonarow GC, Peacock WF, Horwich TB, Phillips CO, Givertz MM, Lopatin M, Wynne J; ADHERE Scientific Advisory Committee and Investigators. Usefulness of B-type natriuretic peptide and cardiac troponin levels to predict in-hospital mortality from ADHERE. Am J Cardiol. 2008 Jan 15;101(2):231-7. Epub 2007 Dec 3.

Hauptman PJ, Goodlin SJ, Lopatin M, Costanzo MR, Fonarow GC, Yancy CW. Characteristics of patients hospitalized with acute decompensated heart failure who are referred for hospice care. Arch Intern Med. 2007 Oct 8;167(18):1990-7.

Fonarow GC, Peacock WF, Phillips CO, Givertz MM, Lopatin M; ADHERE Scientific Advisory Committee and Investigators. Admission B-type natriuretic peptide levels and in-hospital mortality in acute decompensated heart failure. J Am Coll Cardiol. 2007 May 15;49(19):1943-50. Epub 2007 Apr 30.

Study ID Numbers:	CR005194
Study First Received:	August 18, 2006
Last Updated:	January 16, 2008
ClinicalTrials.gov Identifier:	NCT00366639 History of Changes
Health Authority:	United States: Institutional Review Board

Keywords provided by Scios, Inc.:

heart decompensation
Heart failure, congestive

Study placed in the following topic categories:

Heart Failure
Heart Diseases

Additional relevant MeSH terms:

Heart Failure
Heart Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on July 02, 2009