The Role of Endothelium Dysfunction in Progression of CKD (Chronic Kidney Disease) After AKI (Acute Kidney Injury)
To understand how AKI (Acute Kidney Injury) leads to chronic kidney disease so therapies can be found to alter the progression of events thereby significantly impacting the long-term outcomes of children who develop AKI.
Acute Renal Failure
Chronic Kidney Failure
Hemolytic-uremic Syndrome (HUS)
|Study Design:||Observational Model: Cohort
Time Perspective: Cross-Sectional
|Official Title:||The Role of Endothelium Dysfunction in Progression of CKD (Chronic Kidney Disease) After AKI (Acute Kidney Injury)|
|Study Start Date:||April 2008|
|Study Completion Date:||July 2009|
|Primary Completion Date:||July 2009 (Final data collection date for primary outcome measure)|
those with previous history of Acute kidney injury
This research study is designed to study what happens to the kidneys after they have an injury. There is some evidence that even if there appears to be great improvement of kidney function, an injury can put patients at risk for long-term problems with their kidney function and increase their risk to have high blood pressure. We want to collect information from participants to help explain why this injury can cause future problems, including Chronic Kidney Disease (CKD) which may help us prevent these health problems.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00358306
|Principal Investigator:||David Askenazi, MD||UAB Pediatric Nephrology|