Arterial Stiffness, Wave Reflections and Renal Failure
This study has been completed.
Information provided by:
First received: July 19, 2006
Last updated: November 3, 2010
Last verified: November 2010
- Cardiovascular risk is high in patients with renal failure.
- Cross-sectional studies have indicated a relationship between arterial stiffness and renal function. However, there are no prospective longitudinal studies in the literature.
- In dialysis patients, arterial stiffness as well as wave reflections, predict mortality. However, there are no data on patients with mild-to-moderate renal impairment available.
- Therefore, we designed a study to test the hypothesis that: a) measures of arterial stiffness and wave reflections predict the progression of renal impairment in patients with mild-to-moderate renal failure; and b) measures of arterial stiffness and wave reflections predict cardiovascular events in patients with mild-to-moderate renal failure
Chronic Renal Failure
Arterial Wave Reflections
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Observational Study on the Prognostic Significance (Renal and Cardiovascular) of Arterial Stiffness and Arterial Wave Reflections in Patients With Mild to Moderate Renal Impairment|
Resource links provided by NLM:
Further study details as provided by Klinikum Wels-Grieskirchen:
Primary Outcome Measures:
- renal endpoint [ Designated as safety issue: No ]doubling serum creatinine, need for dialysis, renal transplantation
|Study Start Date:||January 2006|
|Study Completion Date:||October 2010|
|Primary Completion Date:||October 2010 (Final data collection date for primary outcome measure)|
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00354588
|Cardiology and Nephrology Department Klinikum Wels|
|Wels, Austria, 4600|
Sponsors and Collaborators
|Principal Investigator:||Thomas Weber, MD||Cardiology Department, Klinikum Wels, Austria|
|Principal Investigator:||Manfred Wallner, MD||Nephrology Department, Klinikum Wels, Austria|