Impact of Anti-HIV Treatment on Labor Productivity and Costs in South Africa

This study has been terminated.
(Enrollment never initiated, study withdrawn.)
Sponsor:
Collaborator:
United States Agency for International Development (USAID)
Information provided by:
Boston University
ClinicalTrials.gov Identifier:
NCT00270725
First received: December 27, 2005
Last updated: March 29, 2011
Last verified: March 2011
  Purpose

The purpose of this study is to determine the impact of anti-HIV treatment on the work attendance of employed people in South Africa. The study will enroll participants from a large manufacturing and distribution firm in South Africa.


Condition
HIV Infections

Study Type: Observational
Official Title: The Effectiveness of Antiretroviral Therapy in Reducing the Costs of HIV/AIDS

Resource links provided by NLM:


Further study details as provided by Boston University:

Estimated Enrollment: 120
Study Start Date: July 2005
Study Completion Date: July 2005
Detailed Description:

Little is known about the economic benefits of providing antiretroviral therapy (ART) for HIV infected patients in sub-Saharan Africa and other resource-limited areas. In South Africa, an increasing number of private sector firms are providing access to ART for their employees. One of the barriers to such action, however, is the lack of available information on the success of ART in restoring workers to full productivity, retaining skilled employees in the workforce, and reducing the costs of medical care and death and disability benefits. HIV infected employees on ART may be absent from work less often than untreated HIV infected employees, but more often than HIV uninfected employees. This study will collect data from an independent HIV/AIDS disease treatment program and a large private sector employer in Johannesburg, South Africa to estimate the benefits and costs for businesses to provide ART to eligible employees.

The study will combine individual-level medical outcome and treatment cost data from the treatment program with data on employee work attendance and retention in the workforce from the participating employer. The work attendance of HIV infected employees enrolled in the HIV/AIDS treatment program (index participants) who are either taking ART or receiving pre-ART care will be compared with each other and with that of HIV uninfected employees. There are no study visits associated with this study; all data will be collected from medical records maintained by the HIV/AIDS treatment program and the participants' employer. The financial costs and benefits of the treatment program for the participating company will also be estimated.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

see elig

Criteria

Inclusion Criteria for All Participants:

  • Employed by participating company for at least 1 year prior to study entry

Inclusion Criteria for Index Participants:

  • Enrolled in the HIV/AIDS treatment program offered by the participating company

Exclusion Criteria for Index Participants:

  • Enrolled in the HIV/AIDS treatment program prior to 01/01/04 or after 06/30/05
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00270725

Locations
South Africa
Health Economics Research Office, Helen Joseph Hospital
Johannesburg, Gauteng, South Africa, 2092
Sponsors and Collaborators
Boston University
United States Agency for International Development (USAID)
Investigators
Principal Investigator: Sydney B. Rosen, MPA Boston University
  More Information

Publications:
Responsible Party: Sydney Rosen, Boston University
ClinicalTrials.gov Identifier: NCT00270725     History of Changes
Other Study ID Numbers: RTC-BU-01
Study First Received: December 27, 2005
Last Updated: March 29, 2011
Health Authority: United States: Institutional Review Board
South Africa: National Health Research Ethics Council

Keywords provided by Boston University:
HIV
AIDS
Labor productivity
Antiretroviral therapy
South Africa

Additional relevant MeSH terms:
HIV Infections
Acquired Immunodeficiency Syndrome
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Slow Virus Diseases

ClinicalTrials.gov processed this record on July 23, 2014