Brain Aging Project--Kansas University
Recruitment status was Active, not recruiting
The purpose of this study is to determine the effects of exercise and cardiorespiratory fitness on age-related brain changes.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||KU Brain Aging Project|
Blood samples are collected analyzed and banked as whole blood, serum, white blood cells
|Study Start Date:||November 2004|
|Estimated Study Completion Date:||December 2009|
|Estimated Primary Completion Date:||December 2009 (Final data collection date for primary outcome measure)|
elderly people who have normal cognition
elderly people who have mild to moderate Alzheimer's disease
The mission of the KU Brain Aging Project is to promote healthy brain aging. How the brain changes with age is not well-characterized and even less is known about the factors influencing the rate of brain aging. Thus, we are using MRI scans to examine the structure of the brain in relation to important lifestyle factors. This will allow us to better understand the processes influencing the brain as it ages. In turn, this will help identify specific ways to promote healthy brain aging and, perhaps, prevent the onset of Alzheimer's disease.
Participants complete 4 visits over several months. The first visit entails a clinical evaluation and memory testing involving the use of paper and pencil testing. The second visit is an MRI brain scan which lasts approximately one hour. The third visit involves drawing blood for laboratory testing and blood banking for future lab studies, lasting roughly 4 hours. The glucose tolerance test is administered. The fourth and final visit is an assessment of the participant's metabolism and exercise testing. This visit lasts approximately two hours.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00267124
|United States, Kansas|
|University of Kansas Medical Center|
|Kansas City, Kansas, United States, 66160|
|Principal Investigator:||Jeffrey Burns, MD||University of Kansas Medical Center, Landon Center on Aging|