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| Sponsors and Collaborators: |
National Institute on Aging (NIA) University of Kansas |
| Information provided by: | National Institute on Aging (NIA) |
| ClinicalTrials.gov Identifier: | NCT00267124 |
Purpose
The purpose of this study is to determine the effects of exercise and cardiorespiratory fitness on age-related brain changes.
| Condition |
|
Alzheimer's Disease |
| Genetics Home Reference related topics: | Alzheimer disease |
| MedlinePlus related topics: | Alzheimer's Caregivers Alzheimer's Disease |
| Study Type: | Observational |
| Study Design: | Longitudinal, Defined Population, Prospective Study |
| Official Title: | KU Brain Aging Project |
| Estimated Enrollment: | 120 |
| Study Start Date: | November 2004 |
The mission of the KU Brain Aging Project is to promote healthy brain aging. How the brain changes with age is not well-characterized and even less is known about the factors influencing the rate of brain aging. Thus, we are using MRI scans to examine the structure of the brain in relation to important lifestyle factors. This will allow us to better understand the processes influencing the brain as it ages. In turn, this will help identify specific ways to promote healthy brain aging and, perhaps, prevent the onset of Alzheimer's disease.
Participants complete 4 visits over several months. The first visit entails a clinical evaluation and memory testing involving the use of paper and pencil testing. The second visit is an MRI brain scan which lasts approximately one hour. The third visit involves drawing blood for laboratory testing and blood banking for future lab studies, lasting roughly 4 hours. The glucose tolerance test is administered. The fourth and final visit is an assessment of the participant's metabolism and exercise testing. This visit lasts approximately two hours.
Eligibility
| Ages Eligible for Study: | 65 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: M. Pat Laubinger, MPA, BSN | 913-588-0685 | plaubinger@kumc.edu |
| United States, Kansas | |||||
| University of Kansas Medical Center | Recruiting | ||||
| Kansas City, Kansas, United States, 66160 | |||||
| Contact: Jeffrey Burns, MD 913-588-0555 jburns2@kumc.edu | |||||
| Contact: M. Pat Laubinger, MPA, BSN 913-588-0685 plaubinger@kumc.edu | |||||
| National Institute on Aging (NIA) |
| University of Kansas |
| Principal Investigator: | Jeffrey Burns, MD | University of Kansas Medical Center, Landon Center on Aging |
More Information
KU Brain Imaging Project 
  |
| Study ID Numbers: | IA0089, 1R03AG026374-01 |
| First Received: | December 16, 2005 |
| Last Updated: | September 19, 2007 |
| ClinicalTrials.gov Identifier: | NCT00267124 |
| Health Authority: | United States: Federal Government |
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