Clinical Outcome of Laparoscopic Versus Open Nissen Fundoplication in Children: 3−Year Follow-up Study of Randomized Controlled Trial.
Long-term results following laparoscopic and open Nissen fundoplication for gastro-oesophageal reflux will be objectively assessed in a selected population of patients already included in a randomized controlled trial comparing the two different techniques. The presence of postoperative symptoms will be evaluated by an independent clinician using an objective questionnaire. The recurrence of gastro-oesophageal reflux will be studied by 24-hours pH study. Furthermore the presence of gastric motility disorders will be studied by electrogastrography and 13C-octanoic acid breath test.
Gastro -Oesophagal Reflux
Procedure: open fundoplication
Procedure: laparoscopic fundopliaction
|Study Design:||Observational Model: Defined Population
Time Perspective: Longitudinal
Please refer to this study by its ClinicalTrials.gov identifier: NCT00259961
|Great Ormond Street Hospital|
|London, United Kingdom|
|Principal Investigator:||Pierro Agostino, Prof||Great Ormond Street Hospital|